PPP1CA

Item no.	enz-165-1ug
Manufacturer	ProSpec
Amount	1 ug
Quantity options	1 ug 50 ug 5 ug
Category	Neuroscience Molecular Targets for Neuroscience Peptides & Proteins Enzymes
Type	Enzymes
Format	Liquid
Specific against	Human (Homo sapiens)
Purity	Greater than 80.0% as determined by SDS-PAGE.
Sequence	MGSSHHHHHH SSGLVPRGSH MSDSEKLNLD SIIGRLLEVQ GSRPGKNVQL TENEIRGLCL KSREIFLSQP ILLELEAPLK ICGDIHGQYY DLLRLFEYGG FPPESNYLFL GDYVDRGKQS LETICLLLAY KIKYPENFFL LRGNHECASI NRIYGFYDEC KRRYNIKLWK TFTDCFNCLP IAAIVDEKIF CCHGGLSPDL QSMEQIRRIM RPTDVPDQGL LCDLLWSDPD KD
ECLASS 10.1	32160410
ECLASS 11.0	32160410
UNSPSC	12352204
Alias	Serine/threonine-protein phosphatase PP1-alpha catalytic subunit,PP-1A,PPP1CA,PPP1A,PP1alpha
Similar products	PPP1CA
Available
Manufacturer - Category	ENZYMES
Storage Conditions	Store at 4C if entire vial will be used within 2-4 weeks. Store, frozen at -20C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Description	Recombinant Human Protein Phosphatase 1, Catalytic Subunit Alpha
Formulation	PPP1CA protein solution (0.25mg/ml) containing 50mM Tris-HCl buffer (pH8.0), 40% glycerol, 0.15M NaCl, 1mM DTT, 0.1mM PMSF and 1mM MnCl₂.
Introduction	Serine/Threonine-protein phosphatase PP1-alpha catalytic subunit (PPP1CA) is crucial for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. The PPP1CA protein may have a significant role in dephosphorylating substrates such as the postsynaptic density-associated Ca²⁺/calmodulin dependent protein kinase II.
Usage	ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Biological Activity	Specific activity: 3, 000 units/mg. Enzymatic activity was confirmed by measuring the amount of enzyme hydrolyzing 1 nmole of p-nitrophenyl phosphate (pNPP) per minute at 37C, pH7.5 using 10mM of substrate.
Manufacturer - Format	Sterile Filtered colorless solution.

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enz-165-1ug-safety-datasheet.pdf