tPA

Item no.	enz-263-20ug
Manufacturer	ProSpec
Amount	20 ug
Quantity options	100 ug 1 mg 20 ug
Category	Food Safety Proteins Peptides & Proteins Enzymes
Type	Enzymes
Format	Lyophilized
Specific against	Human (Homo sapiens)
Purity	Greater than 98.0% as determined by:<BR>(a) Analysis by RP-HPLC.<BR>(b) Analysis by SDS-PAGE.
ECLASS 10.1	32160410
ECLASS 11.0	32160410
UNSPSC	12352204
Alias	tPA,Tissue-type plasminogen activator,EC 3 4 21 68,tPA,t-PA,t-plasminogen activator,TPA,T-PA,DKFZp686I03148
Similar products	tPA
Available
Manufacturer - Category	ENZYMES
Storage Conditions	Lyophilized t-PA although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution tPA should be stored at 4C between 2-7 days and for future use below -18C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Description	Recombinant Human Tissue Plasminogen Activator
Formulation	Each mg of t-PA contains 1.7 gr L-arginine, 0.5 gr phosphoric acid and 4 mg tween 80.
Introduction	Tissue plasminogen activator (abbreviated PLAT or tPA) is a secreted serine proteasewhich converts the proenzymeplasminogento plasmin, a fibrinolyticenzyme. Plasminogen is synthesized as a single chain which is cleaved by PLAT into the two chain disulfide linked plasmin. This enzyme plays a role in cell migrationand tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, decreased activity leads to hypofibrinolysiswhich can result in thrombosisor embolism.
Usage	ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Manufacturer - Format	Sterile Filtered White lyophilized (freeze-dried) powder.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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enz-263-20ug-safety-datasheet.pdf