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PLA2G1B

PLA2G1B

Item no.	enz-325-1mg
Manufacturer	ProSpec
Amount	1 mg
Quantity options	10 ug 1 mg 2 ug
Category	Metabolism Cholesterol & Lipid Metabolism Peptides & Proteins Enzymes
Type	Enzymes
Format	Lyophilized
Specific against	Human (Homo sapiens)
Purity	Greater than 95% as determined by SDS-PAGE.
ECLASS 10.1	32160410
ECLASS 11.0	32160410
UNSPSC	12352204
Alias	PLA2G1B,Phospholipase A2,EC 3 1 1 4,Phosphatidylcholine 2-acylhydrolase,Group IB phospholipase A2,PLA2,PLA2A,PPLA2,sPLA2-IB,MGC119834,MGC119835,PLA2G1B
Similar products	PLA2G1B
Available
Manufacturer - Category	ENZYMES
Storage Conditions	Store lyophilized protein at -20C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4C for a limited period of time, it does not show any change after two weeks at 4C.
Description	Recombinant Human Secreted Phospholipase A2-IB
Formulation	Filtered (0.4um) and lyophilized from 0.5 mg/ml in 0.05M Acetate buffer pH-4.
Introduction	Group IB secretory phospholipase A2 (sPLA2-IB) mediates cell proliferation, cell migration, hormone release and eicosanoid production via its receptor in peripheral tissues. In the CNS, high-affinity binding sites of sPLA2-IB have been documented. sPLA2-IB induced neuronal cell death in a concentrationdependent manner depending on PGD2 metabolites, especially Delta12-PGJ2 that might mediate sPLA2-IB-induced apoptosis. The secretory PLA2 (sPLA2) family, in which 10 isozymes have been identified, consists of lowmolecular weight, Ca2+-requiring secretory enzymes that have been implicated in a number of biological processes, such as modification of eicosanoid generation, inflammation, and host defense.
Usage	ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Manufacturer - Format	Lyophilized (freeze-dried) powder.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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enz-325-1mg-safety-datasheet.pdf