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SERPINE1

SERPINE1

Item no.	enz-357-25ug
Manufacturer	ProSpec
Amount	25 ug
Quantity options	1 mg 25 ug 5 ug
Category	Food Safety Proteins Peptides & Proteins Enzymes
Type	Enzymes
Format	Liquid
Specific against	Human (Homo sapiens)
Purity	Greater than 95.0% as determined by SDS-PAGE.
Sequence	MGSSHHHHHH SSGLVPRGSH MVHHPPSYVA HLASDFGVRV FQQVAQASKD RNVVFSPYGVASVLAMLQLT TGGETQQQIQ AAMGFKIDDK GMAPALRHLY KELMGPWNKD EISTTDAIFVQRDLKLVQGF MPHFFRLFRS TVKQVDFSEV ERARFIINDW VKTHTKGMIS NLLGKGAVDQLTRLVLVNAL YFNGQWKTPF PDSSTHRRLF HKSDGSTVSV PMMAQTNKFN YTEFT
ECLASS 10.1	32160410
ECLASS 11.0	32160410
UNSPSC	12352204
Alias	SERPINE1,PAI-1,PAI1,PLANH1,SERPINE1,PAIE,PLASMINOGEN ACTIVATOR INHIBITOR,BETA-MIGRATING ENDOTHELIAL-CELL-DERIVED TYPE
Similar products	SERPINE1
Available
Manufacturer - Category	ENZYMES
Storage Conditions	Store at 4C if entire vial will be used within 2-4 weeks. Store, frozen at -20C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Description	Recombinant Human Plasminogen Activator Inhibitor-1
Formulation	150mM Na2HPO4, pH 6.6, 0.5mM NaCl, 2mM Glutathione and 0.01% Tween-80.
Introduction	Plasminogen activator inhibitor-1 is the principal inhibitor of tissue plasminogen activator(tPA) and urokinase(uPA), the activators of plasminogenand hence fibrinolysis(the physiological breakdown of blood clots). It is a serine protease inhibitor(serpin) protein (SERPINE1). The other PAI, plasminogen activator inhibitor-2(PAI-2) is secreted by the placentaand only present in significant amounts during pregnancy. In addition, protease nexinacts as an inhibitor of tPA and urokinase. SERPINE1, however, is the main inhibitor of the plasminogen activators.
Usage	ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Manufacturer - Format	Sterile Filtered clear colorless solution.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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enz-357-25ug-safety-datasheet.pdf