MAOB

Item no.	enz-440-10ug
Manufacturer	ProSpec
Amount	10 ug
Quantity options	10 ug 1 mg 2 ug
Category	Neuroscience Molecular Targets for Neuroscience Peptides & Proteins Enzymes
Type	Enzymes
Format	Liquid
Specific against	Human (Homo sapiens)
Purity	Greater than 95.0% as determined by SDS-PAGE.
ECLASS 10.1	32160410
ECLASS 11.0	32160410
UNSPSC	12352204
Alias	MAOB,Amine oxidase [flavin-containing] B,Monoamine oxidase type B,MAO-B,MAOB,MGC26382
Similar products	MAO-B
Available
Manufacturer - Category	ENZYMES
Storage Conditions	Store at 4C if entire vial will be used within 2-4 weeks. Store, frozen at -20C for longer periods of time. Please avoid freeze thaw cycles.
Description	Recombinant Human Monoamine Oxidase B
Formulation	MAO-B protein is supplied in 20mM Tris-HCl, pH 8.0, 250mM NaCl, 1mM EDTA and 50% glycerol.
Introduction	MAO-B is a member of the flavin monoamine oxidase family. MAO-B (Monoamine oxidase B) is a flavin-containing mitochondrial enzyme that catalyzes the oxidative deamination of biogenic and xenobiotic monoamines. MAO-B controls the metabolic degradation of catecholamines and serotonin in neural and other target tissues. MAO-B is located in platelets and in dopamine-secreting neurons in the brain. MAOB and MAOA genes have an imperative function in dopamine degradation. Benzylamine and phenylethylamine are preferentially degraded by MAOB. The MAOB gene is linked to autistic traits, empathy and Asperger syndrome. Amplified levels of MAO B are identified in the brain of Alzheimers patients. High phenylethylamine levels in neonates as a result of low MAOB are consistent with phenylketonuria in newborns. Polymorphisms in MAO-B are connected to smoking behavior.
Usage	ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Manufacturer - Format	Sterile Filtered clear solution.

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