ENPP1

Item no.	enz-729-10ug
Manufacturer	ProSpec
Amount	10 ug
Quantity options	10 ug 1 mg 2 ug
Category	Metabolism Diabetes Cholesterol & Lipid Metabolism Regulation of Appetite Peptides & Proteins Recombinant Proteins
Type	Proteins
Format	Lyophilized
Specific against	Human (Homo sapiens)
Purity	Purity as determined by densitometric image analysis is greater than 95%.
Sequence	AS KPSCAKEV KSCKGRCFER TFGNCRCDAA CVELGNCCLD YQETCIEPEH IWTCNKFRCG EKRLTRSLCA CSDDCKDKGD CCINYSSVCQ GEKSWVEEPC ESINEPQCPA GFETPPTLLF SLDGFRAEYL HTWGGLLPVI SKLKKCGTYT KNMRPVYPTK TFPNHYSIVT GLYPESHGII DNKMYDPKMN ASFSLKSKEK FNPEWYKGEP IWVTAKYQGL KSGTFFWPGS D
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	ENPP1,Ectonucleotide pyrophosphatase/phosphodiesterase family member 1,E-NPP 1,Membrane component chromosome 6 surface marker 1,Phosphodiesterase I/nucleotide pyrophosphatase 1,Plasma-cell membrane glycoprotein PC-1,ENPP1,M6S1,NPPS,PC1,PDNP1,NPP1,PC-1,PCA1,ARHR2,COLED
Available
Manufacturer - Category	ENZYMES
Storage Conditions	Store lyophilized protein at -20C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4C for a limited period of time.
Description	Recombinant Human Ectonucleotide Pyrophosphatase
Formulation	Filtered (0.4um) and lyophilized from 0.5mg/ml in 0.05M phosphate buffer and 0.075M NaCl, pH 7.4.
Introduction	Ectonucleotide Pyrophosphatase (ENPP1) belongs to the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family. ENPP1 is a type II transmembrane glycoprotein comprised of 2 identical disulfide-bonded subunits. The ENPP1 protein has broad specificity and cleaves various substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds of nucleotides and nucleotide sugars. The ENPP1 protein can hydrolyze nucleoside 5' triphosphates to their corresponding monophosphates and it may also hydrolyze diadenosine polyphosphates. ENPP1 gene mutations are linked with 'idiopathic' infantile arterial calcification, ossification of the posterior longitudinal ligament of the spine (OPLL), and insulin resistance.
Usage	ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Manufacturer - Format	Filtered lyophilized (freeze-dried) powder.

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enz-729-10ug-safety-datasheet.pdf