STC2

Item no.	hor-296-10ug
Manufacturer	ProSpec
Amount	10 ug
Quantity options	100 ug 10 ug 2 ug
Category	Food Safety Allergenes Peptides & Proteins Recombinant Proteins
Type	Hormones
Format	Lyophilized
Specific against	Human (Homo sapiens)
Purity	Greater than 90.0% as determined by SDS-PAGE.
Sequence	TDATNPPEGP QDRSSQQKGR LSLQNTAEIQ HCLVNAGDVG CGVFECFENN SCEIRGLHGI CMTFLHNAGKFDAQGKSFIK DALKCKAHAL RHRFGCISRK CPAIREMVSQ LQRECYLKHD LCAAAQENTR VIVEMIHFKDLLLHEPYVDL VNLLLTCGEE VKEAITHSVQ VQCEQNWGSL CSILSFCTSA IQKPPTAPPE RQPQVDRTKLSRAHHGEAGH HLPEPSSRET GRGAK
ECLASS 10.1	42021503
ECLASS 11.0	42021503
UNSPSC	41116126
Alias	STC2,Stanniocalcin-2,STC,STC2,STCRP,STC-2,Stanniocalcin-related protein,STC-related protein
Similar products	STC 2
Available
Manufacturer - Category	HORMONES
Storage Conditions	Lyophilized STC-2 although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution Stanniocalcin should be stored at 4C between 2-7 days and for future use below -18C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Description	Recombinant Human Stanniocalcin-2
Formulation	Filtered (0.4um) and lyophilized in 0.5 mg/ml in 20mM Tris buffer, 20mM NaCl, pH 7.5.
Introduction	STC2 is a homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive over expression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression of this gene is induced by estrogen and altered in some breast cancers.
Usage	ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Manufacturer - Format	White lyophilized (freeze-dried) powder.

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