ST13

Item no.	hsp-130-10ug
Manufacturer	ProSpec
Amount	10 ug
Quantity options	10 ug 1 mg 50 ug
Category	Food Safety Hormones Neuroscience Neuroinflammation Protein Aggregation, Clearance & Misfolding Peptides & Proteins Recombinant Proteins
Type	Proteins
Format	Liquid
Specific against	Human (Homo sapiens)
Purity	Greater than 90.0% as determined by SDS-PAGE.
Sequence	MDPRKVNELR AFVKMCKQDP SVLHTEEMRF LREWVESMGG KVPPATQKAK SEENTKEEKP DSKKVEEDLK ADEPSSEESD LEIDKEGVIEPDTDAPQEMG DENAEITEEM MDQANDKKVA AIEALNDGEL QKAIDLFTDA IKLNPRLAIL YAKRASVFVK LQKPNAAIRD CDRAIEINPD SAQPYKWRGK AHRLLGHWEE AAHDLALACK LDYDEDASAM LKEVQPRAQK IAE
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	ST13,AAG2,SNC6,HSPABP,FAM10A1,FAM10A4,HSPABP1,ST-13,Hsc70-interacting protein,Suppression of tumorigenicity protein 13,Putative tumor suppressor ST13,Protein FAM10A1,Progesterone receptor-associated p48 protein,Renal carcinoma antigen NY-REN-33,ST13,HIP,HOP,P48,PRO0786,FLJ27260,MGC129952
Similar products	ST13
Available
Manufacturer - Category	HEAT SHOCK PROTEINS
Storage Conditions	Store at 4C if entire vial will be used within 2-4 weeks. Store, frozen at -20C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Description	Recombinant Human HSP70 Interacting Protein
Formulation	The ST13 protein solution contains 20mM Tris-HCl, pH-8 1mM DTT, 0.1M NaCl & 10% Glycerol.
Introduction	ST13 is an adaptor protein (co-chaperone) that mediates the association of HSP70 & HSP90 and appears in early receptor complexes. ST13 plays a role in the assembly process of glucocorticoid receptor, which requires the assistance of multiple molecular chaperones. The expression of ST13 is downregulated in colorectal carcinoma tissue signifying that is candidate tumor suppressor gene. Through common binding to both Hsp70 and Hsp90, ST13 functions as an adaptor that can integrate Hsp70 and Hsp90 interactions. The expression of ST13 decreases in colorectal cancer tissue compared with that in adjacent normal tissue. ST13 is mostly expressed in colorectal epithelia and adenocarcinoma cells. ST13 functions to promote the efficiency of glucocorticoid receptor maturation in cells. The expression levels of the ST13 gene were significantly decreased in primary tumors compared with adjacent mucosa.
Usage	ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Manufacturer - Format	Sterile filtered colorless solution.

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hsp-130-10ug-safety-datasheet.pdf