BCL2L2

Item no.	pro-1577-1mg
Manufacturer	ProSpec
Amount	1 mg
Quantity options	1 mg 20 ug 5 ug
Category	Food Safety Drugs Neuroscience Neural Lineage Markers Metabolism Diabetes Glucose Homeostasis Molecular Targets for Neuroscience Targets for Rodent Neurosciences Neural Signaling Peptides & Proteins Recombinant Proteins Neuronal Cell Markers
Type	Proteins
Format	Liquid
Specific against	Human (Homo sapiens)
Purity	Greater than 95.0% as determined by:<BR>(a) Analysis by RP-HPLC.<BR>(b) Analysis by SDS-PAGE.
Sequence	ATPASAPDTR ALVADFVGYK LRQKGYVCGA GPGEGPAADP LHQAMRAAGD EFETRFRRTF SDLAAQLHVT PGSAQQRFTQ VSDELFQGGP NWGRLVAFFV FGAALCAESV NKEMEPLVGQ VQEWMVAYLE TQLADWIHSS GGWAEFTALY GDGALEEARR LREGNWASVR T
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	BCL2L2,B-Cell Lymphoma Protein 2,BCL2 Like 2,BCL2 Like protein 2,BCLW,Bcl2-L-2,Apoptosis regulator Bcl-W,BCL2L2,BCL-W,KIAA0271
Available
Manufacturer - Category	RECOMBINANT & NATURAL PROTEINS
Storage Conditions	BCL2L2 although stable at room temperature for 3 weeks, should be stored at 4C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Description	Recombinant Human BCL2 Like 2
Formulation	BCL2L2 is a0.2um filtered concentrated solution which contains 25 mM Hepes, pH 7.4, 100 mM KCl, 10 % Glycerol, 5 % Trehalose, and 0.02 % Tween-80.
Introduction	BCL2L2 promotes cell survival and blocks dexamethasone-induced apoptosis. BCL2L2 mediates survival of postmitotic Sertoli cells by suppressing death-promoting activity of BAX. BCL2L2 is part of the BCL-2 protein family which form hetero- or homodimers and play an important role as anti and proapoptotic regulators. BCL2L2 causes reduced cell apoptosis under cytotoxic conditions. BCL2L2 is involved in the survival of NGF- and BDNF-dependent neurons. BCL2L2 plays an important role in adult spermatogenesis.
Usage	ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Manufacturer - Format	Sterile Filtered clear solution.

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pro-1577-1mg-safety-datasheet.pdf