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Intrinsic Factor

Intrinsic Factor

Item no.	pro-375-2ug
Manufacturer	ProSpec
Amount	2 ug
Quantity options	10 ug 1 mg 2 ug
Category	Food Safety Vitamines Peptides & Proteins Recombinant Proteins
Type	Proteins
Format	Liquid
Specific against	Human (Homo sapiens)
Purity	Greater than 95.0% as determined by:<BR>(a) Analysis by RP-HPLC.<BR>(b) Analysis by SDS-PAGE.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Intrinsic Factor,Gastric intrinsic factor,Intrinsic factor,INF,IF,GIF,IFMH,TCN3,Cobalamin/Vitamin B-12 binding transport protein
Similar products	Intrinsic Factor
Available
Manufacturer - Category	RECOMBINANT & NATURAL PROTEINS
Storage Conditions	Store at 4C if entire vial will be used within 2-4 weeks. Store, frozen at -20C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Description	Recombinant Human Intrinsic Factor
Formulation	The protein solution (0.7mg/ml) contains 20mM HEPES pH-8, 100mM NaCl, 20% Glycerol.
Introduction	Intrinsic Factor is a member of the cobalamin transport protein family. It encodes a glycoprotein secreted by parietal cells of the gastric mucosa and is required for adequate absorption of vitamin B12 in the terminal ileum. Vitamin B12 is essential for erythrocyte maturation and mutations in the Intrinsic Factor may lead to congenital pernicious anemia. Upon entry into the stomach, vitamin B12 binds to one of two B12 binding proteins present in the gastric fluid. In the less acidic environment of the small intestine, these proteins dissociate from the vitamin, allowing it to bind to intrinsic factor and enter the portal circulation through a receptor in the ileal mucosa specific for the B12-intrinsic factor complex.
Usage	ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Manufacturer - Format	Sterile Filtered pink solution. (The reactivity of the antigen is about 10 times higher when adding vitamin B12).

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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pro-375-2ug-safety-datasheet.pdf