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Angiotensin

Angiotensin

Item no.	enz-283-200mg
Manufacturer	ProSpec
Amount	200mg
Category	Neuroscience Aging & Neurological Disorders Peptides & Proteins Enzymes
Type	Enzymes
Specific against	other
ECLASS 10.1	32160410
ECLASS 11.0	32160410
UNSPSC	12352204
Similar products	Angiotensin
Available
Synonyms	Angiotensinogen, Serpin A8, ANHU, SERPINA8
Introduction	Angiotensin is an oligopeptide in the blood that causes vasoconstriction, increased blood pressure, and release of aldosterone from the adrenal cortex. It is a powerful dipsogen. It is derived from the precursor molecule angiotensinogen, a serum globulin produced in the liver. It plays an important role in the renin-angiotensin system. The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia.
Description	Angiotensin contains a total of 8 amino acids having a molecular weight of 1031.2 Dalton and a molecular formula of C₄₉H₇₀N₁₄O₁₁.
Source	Synthetic.
Physical Appearance	Sterile Filtered white lyophilized powder.
Purity	Greater than 98.0% as determined by RP-HPLC.
Usage	ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Amino acid sequence	Asn-Arg-Val-Tyr-Val-His-Pro-Phe-OH.
Storage	Lyophilized Angiotensin although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution Serpin A8 should be stored at 4C between 2-7 days and for future use below -18C. Please prevent freeze-thaw cycles.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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enz-283-200mg-safety-datasheet.pdf