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SARS-CoV-2 (COVID-19) Full-Length Gamma Variant (P.1, Brazil) Spike Recombinant Protein

SARS-CoV-2 (COVID-19) Full-Length Gamma Variant (P.1, Brazil) Spike Recombinant Protein

Item no.	21-820-0.025mg
Manufacturer	Sino Biological
Amount	0.025 mg
Category	Peptides & Proteins Recombinant Proteins ELISA Immunostaining
Type	Proteins Recombinant
Format	Liquid
Applications	ELISA
Specific against	SARS-CoV-2
Host	HEK293 cells
Conjugate/Tag	Rho1d4
Purity	>98% as determined by SDS-PAGE, see Fig. 1 A and B. PureCube Rho1D4 Agarose.
Dry ice	Yes
Sequence	Full-length sequence (aa 1 – 1273), L18F, T20N, P26S, D138Y, R190S, K417T, E484K, N501Y, H655Y,<br>T1027I, V1176F<br>furin cleavage site “RRAR” mutated to “GSAG”; KV986PP<br>C-terminal Rho1D4 tag fused with spacer “GSSG” to protein sequence
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	SARS-CoV-2 (COVID-19) Spike Recombinant Protein: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),Surface Glycoprotein,Spike protein
Available
Manufacturer - Conjugate / Tag	C-terminal Rho1D4
Storage Conditions	–80˚ C. Avoid freeze-thaw cycles
Buffer	20 mM Hepes pH 7.5; 150 mM NaCl, 0.001 % LMNG
Bio-Activity	not determined
Background	All viruses undergo fast mutations and adapt quickly to the countermeasures that the immune systems creates. SARS-CoV-2 of the COVID-19 pandemic is no exception to this. During the pandemic multiple mutant strains arose. To help the sciencific community to combat these mutants ProSci offers the SPIKE protein of the mutants in full-length and active in their native trimeric form, stabilized with the LMNG detergent.; This is the spike protein of the mutant strain P.1, also commonly known as the "Brazil".
Application notes	This recombinant protein can be used for ELISA assays, Ligand binding assays (e.g. SPR), Biochemical and biophysical analyses. For research use only.
Research Area	Infectious Disease, COVID-19
Predicted Molecular Weight	1286 amino acids (including Rho1D4 tag and linker); 142114 Da
Disclaimer	Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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