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Biotinylated Human ANGPTL7 / CDT6 Protein, Mouse IgG2a Fc,Avitag™

Biotinylated Human ANGPTL7 / CDT6 Protein, Mouse IgG2a Fc,Avitag™

Item no.	AN7-H82F3-200ug
Manufacturer	ACROBiosystems
Amount	100 ug x 2
Quantity options	100 ug x 2 25 ug
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Solid
Specific against	Human (Homo sapiens)
Host	HEK293
Isotype	IgG2a
Conjugate/Tag	Biotin, C-mFc, Avi
Purity	90%
Citations	(1) Peek R., et al., 1998, Invest. Opthalmol. Visual Sci. 39 (10): 1782-1788. (2) Peek R., et al., 2002, J. Biol. Chem. 277 (1): 686-693. (3) Kuchtey, J. et al., 2008, Invest. Opthalmol. Visual Sci. 49 (8): 3438-3448.
NCBI	NP_066969.1
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	ANGPTL7,CDT6
Shipping Condition	Room temperature
Available
Manufacturer - Category	Protein
Manufacturer - Conjugate / Tag	C-mFc(mIgG2a) & C-Avi, Biotin-labeled
Shipping Temperature	RT
Storage Conditions	-20°C
Molecular Weight	65.8 kDa
Manufacturer - Format	Powder
Description	Angiopoietin-like 7 (ANGPTL7) is also known as Corneal-Derived Transcript 6 (CDT6), and is a secreted glycoprotein that is structurally related to the angiopoietins. It is expressed in the corneal stroma, trabecular meshwork, and sclera and is elevated in glaucoma aqueous humor. Recently, ANGPTL proteins, including ANGPTL-2, -3, -4, -5 and -7, are identified as growth factors in combination with SCF, Thrombopoietin, IGF-II and FGF acidic that enhance the expansion and engraftment of human and mouse hematopoietic stem cells.
Background	Angiopoietin-like 7 (ANGPTL7) is also known as Corneal-Derived Transcript 6 (CDT6), and is a secreted glycoprotein that is structurally related to the angiopoietins. It is expressed in the corneal stroma, trabecular meshwork, and sclera and is elevated in glaucoma aqueous humor. Recently, ANGPTL proteins, including ANGPTL-2, -3, -4, -5 and -7, are identified as growth factors in combination with SCF, Thrombopoietin, IGF-II and FGF acidic that enhance the expansion and engraftment of human and mouse hematopoietic stem cells.
Molecule	ANGPTL7
Exp Region	Gln 27 - Pro 346
Characteristics	This protein carries a mouse IgG2a Fc tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 65.8 kDa. The protein migrates as 60 kDa and 70 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	Tris with Glycine, Arginine and NaCl, pH7.5
Stability	● -20°C to -70°C for 12 months in lyophilized state ● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant	trehalose

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

AN7-H82F3-200ug-datasheet.pdf

AN7-H82F3-200ug-safety-datasheet.pdf