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MECR, 54-373aa, Human, His tag, E.coli

MECR, 54-373aa, Human, His tag, E.coli

Item no.	ARP-01-1866-250
Manufacturer	American Research Products
Amount	250 ug
Quantity options	10 ug 250 ug 50 ug
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Specific against	other
Purity	> 90% by SDS - PAGE
Sequence	MGSSHHHHHH SSGLVPRGSH MPAKVVELKN LELAAVRGSD VRVKMLAAPI NPSDINMIQG NYGLLPELPA VGGNEGVAQV VAVGSNVTGL KPGDWVIPAN AGLGTWRTEA VFSEEALIQV PSDIPLQSAA TLGVNPCTAY RMLMDFEQLQ PGDSVIQNAS NSGVGQAVIQ IAAALGLRTI NVVRDRPDIQ KLSDRLKSLG AEHVITEEEL RRPEMKNFFK DMPQPRLALN CV
Citations	Scicluna EA., et al. (2010) Eur J Clin Microbiol Infect Dis. 29(2):163-70.Chen ZJ., et al. (2008) J Mol Biol. 379(4):830-44.
NCBI	AAH01419
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	NRBF1, CGI-63, FASN2B, Trans-2-enoyl-CoA reductase, mitochondrial, HsNrbf1, CGI 63, Homolog of yeast 2 enoyl thioester reductase, NBRF 1, NBRF1, NRBF 1, NRBF1, Nuclear receptor binding factor 1
Available
Description	MECR(Mitochondrial trans-2-enoyl-CoA reductase), also known as NRBF1, catalyzes the reduction of trans-2-enoyl-CoA to acyl-CoA with chain length from C6 to C16 in an NADPH dependent manner with preference to medium chain length substrate. This protein has a role in the mitochondrial synthesis of fatty acids. Recombinant human MECR protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques
Form	Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.2M NaCl, 5mM DTT, 20% glycerol
Storage	Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Synonyms	NRBF1, CGI-63, FASN2B, Trans-2-enoyl-CoA reductase, mitochondrial, HsNrbf1, CGI 63, Homolog of yeast 2 enoyl thioester reductase, NBRF 1, NBRF1, NRBF 1, NRBF1, Nuclear receptor binding factor 1
Concentration	0.25 mg/ml (determined by Bradford assay)
NCBI	AAH01419
References	Scicluna EA., et al. (2010) Eur J Clin Microbiol Infect Dis. 29(2):163-70. Chen ZJ., et al. (2008) J Mol Biol. 379(4):830-44.
Antigen Recognized in Species	Human
Purity	>, 90% by SDS - PAGE
Molecular Weight	36.9 kDa (341aa) confirmed by MALDI-TOF
Amino Acid Sequence	MGSSHHHHHH SSGLVPRGSH MPAKVVELKN LELAAVRGSD VRVKMLAAPI NPSDINMIQG NYGLLPELPA VGGNEGVAQV VAVGSNVTGL KPGDWVIPAN AGLGTWRTEA VFSEEALIQV PSDIPLQSAA TLGVNPCTAY RMLMDFEQLQ PGDSVIQNAS NSGVGQAVIQ IAAALGLRTI NVVRDRPDIQ KLSDRLKSLG AEHVITEEEL RRPEMKNFFK DMPQPRLALN CVGGKSSTEL LRQLARGGTM VTYGGMAKQP VVASVSLLIF KDLKLRGFWL SQWKKDHSPD QFKELILTLC DLIRRGQLTA PACSQVPLQD YQSALEASMK PFISSKQILT M
Gene Category	Enzymes

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 250 ug

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Delivery expected until 8/21/2025

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