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CDKN3, 1-212aa, Human, His tag, E.coli

CDKN3, 1-212aa, Human, His tag, E.coli

Item no.	ARP-01-CDK-N3-0.5
Manufacturer	American Research Products
Amount	0.5 mg
Quantity options	0.5 mg 20 ug 50 ug
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Specific against	other
Purity	> 90% by SDS - PAGE
Sequence	MGSSHHHHHH SSGLVPRGSH MKPPSSIQTS EFDSSDEEPI EDEQTPIHIS WLSLSRVNCS QFLGLCALPG CKFKDVRRNV QKDTEELKSC GIQDIFVFCT RGELSKYRVP NLLDLYQQCG IITHHHPIAD GGTPDIASCC EIMEELTTCL KNYRKTLIHC YGGLGRSCLV AACLLLYLSD TISPEQAIDS LRDLRGSGAI QTIKQYNYLH EFRDKLAAHL SSRDSQSRSV SR
Citations	Maak S., et al. (2003) Genet Sel Evol. 1:157-165.Gyuris J., et al. (1993) Cell. 75:791-803.
NCBI	NP_005183
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Cyclin-dependent kinase inhibitor 3, CDI1, CIP2, KAP, KAP1
Available
Description	Cyclin-dependent kinase inhibitor 3, also known CDKN3, belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. Also CDKN3 is important in cell cycle regulation. Recombinant human CDKN3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Form	Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 40% glycerol, 0.1M NaCl
Storage	Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Synonyms	Cyclin-dependent kinase inhibitor 3, CDI1, CIP2, KAP, KAP1
Concentration	0.5 mg/ml (determined by Bradford assay)
NCBI	NP_005183
References	Maak S., et al. (2003) Genet Sel Evol. 1:157-165. Gyuris J., et al. (1993) Cell. 75:791-803.
Antigen Recognized in Species	Human
Purity	>, 90% by SDS - PAGE
Molecular Weight	25.9 kDa (232aa), confirmed by MALDI-TOF
Amino Acid Sequence	MGSSHHHHHH SSGLVPRGSH MKPPSSIQTS EFDSSDEEPI EDEQTPIHIS WLSLSRVNCS QFLGLCALPG CKFKDVRRNV QKDTEELKSC GIQDIFVFCT RGELSKYRVP NLLDLYQQCG IITHHHPIAD GGTPDIASCC EIMEELTTCL KNYRKTLIHC YGGLGRSCLV AACLLLYLSD TISPEQAIDS LRDLRGSGAI QTIKQYNYLH EFRDKLAAHL SSRDSQSRSV SR
Gene Category	Cell Cycle

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.5 mg

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Delivery expected until 9/18/2025

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