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TFB1M, 28-346aa, Human, His tag, E.coli

TFB1M, 28-346aa, Human, His tag, E.coli

Item no.	ARP-01-P1165-10
Manufacturer	American Research Products
Amount	10 ug
Quantity options	10 ug 250 ug 50 ug
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Specific against	other
Purity	> 90% by SDS - PAGE
Sequence	MGSSHHHHHH SSGLVPRGSH MQAAKQLSQN FLLDLRLTDK IVRKAGNLTN AYVYEVGPGP GGITRSILNA DVAELLVVEK DTRFIPGLQM LSDAAPGKLR IVHGDVLTFK VEKAFSESLK RPWEDDPPNV HIIGNLPFSV STPLIIKWLE NISCRDGPFV YGRTQMTLTF QKEVAERLAA NTGSKQRSRL SVMAQYLCNV RHIFTIPGQA FVPKPEVDVG VVHFTPLIQP KI
Citations	McCulloch V., et al. (2002) Mol. Cell. Biol. 22:1116-1125Gleyzer N., et al. (2005) Mol. Cell. Biol. 25(4):1354-66
NCBI	NP_057104
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Dimethyladenosine transferase 1, TFB1M (Mitochondrial transcription factor B1)
Available
Description	TFB1M belongs to the methyltransferase superfamily. TFB1M is a dimethyltransferase that methylates mitochondrial 12S rRNA at the conserved stem loop. This protein also is part of the basal mitochondrial transcription complex and is necessary for mitochondrial gene expression. TFB1M stimulates transcription independently of the methyltransferase activity. Recombinant human TFB1M protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
Form	Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT
Storage	Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Synonyms	Dimethyladenosine transferase 1, TFB1M (Mitochondrial transcription factor B1)
Concentration	0.5 mg/ml (determined by Bradford assay)
NCBI	NP_057104
References	McCulloch V., et al. (2002) Mol. Cell. Biol. 22:1116-1125 Gleyzer N., et al. (2005) Mol. Cell. Biol. 25(4):1354-66
Antigen Recognized in Species	Human
Purity	>, 90% by SDS - PAGE
Molecular Weight	38.8 kDa (340aa), confirmed by MALDI-TOF
Amino Acid Sequence	MGSSHHHHHH SSGLVPRGSH MQAAKQLSQN FLLDLRLTDK IVRKAGNLTN AYVYEVGPGP GGITRSILNA DVAELLVVEK DTRFIPGLQM LSDAAPGKLR IVHGDVLTFK VEKAFSESLK RPWEDDPPNV HIIGNLPFSV STPLIIKWLE NISCRDGPFV YGRTQMTLTF QKEVAERLAA NTGSKQRSRL SVMAQYLCNV RHIFTIPGQA FVPKPEVDVG VVHFTPLIQP KIEQPFKLVE KVVQNVFQFR RKYCHRGLRM LFPEAQRLES TGRLLELADI DPTLRPRQLS ISHFKSLCDV YRKMCDEDPQ LFAYNFREEL KRRKSKNEEK EEDDAENYRL
Gene Category	Transcription and Translation

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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Amount: 10 ug

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Delivery expected until 9/18/2025

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