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THAP1, 1-213 aa , Human, His tag, E.coli

THAP1, 1-213 aa , Human, His tag, E.coli

Item no.	ARP-01-P1517-50
Manufacturer	American Research Products
Amount	50 ug
Quantity options	0.5 mg 20 ug 50 ug
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Specific against	other
Purity	> 85% by SDS - PAGE
Sequence	MGSSHHHHHH SSGLVPRGSH MGSHMVQSCS AYGCKNRYDK DKPVSFHKFP LTRPSLCKEW EAAVRRKNFK PTKYSSICSE HFTPDCFKRE CNNKLLKENA VPTIFLCTEP HDKKEDLLEP QEQLPPPPLP PPVSQVDAAI GLLMPPLQTP VNLSVFCDHN YTVEDTMHQR KRIHQLEQQV EKLRKKLKTA QQRCRRQERQ LEKLKEVVHF QKEKDDVSER GYVILPNDYF EI
Citations	Roussigne M., et al. (2003) Oncogene 22:2432-2442.Clouaire T., et al. (2005) Proc Natl Acad Sci. 102:6907-6912.
NCBI	NP_060575
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	THAP domain-containing protein 1, DYT6
Available
Description	THAP domain-containing protein 1, also known as THAP1, is a 213 amino acid protein that localizes to the nucleoplasm and contains one THAPtype zinc finger, a conserved DNA-binding domain. It is a DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. THAP1 may also have pro-apoptopic activity by potentiating both serum-withdrawal and TNF-induced apoptosis. Recombinant human THAP1protein, fused to His-tag at N-terminus, was expressed in E.coli.
Form	Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2M Urea, 10% glycerol, 1mM DTT, 0.2M NaCl
Storage	Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Synonyms	THAP domain-containing protein 1, DYT6
Concentration	1 mg/ml (determined by Bradford assay)
NCBI	NP_060575
References	Roussigne M., et al. (2003) Oncogene 22:2432-2442. Clouaire T., et al. (2005) Proc Natl Acad Sci. 102:6907-6912.
Antigen Recognized in Species	Human
Purity	>, 85% by SDS - PAGE
Molecular Weight	27.5 kDa (237aa)
Amino Acid Sequence	MGSSHHHHHH SSGLVPRGSH MGSHMVQSCS AYGCKNRYDK DKPVSFHKFP LTRPSLCKEW EAAVRRKNFK PTKYSSICSE HFTPDCFKRE CNNKLLKENA VPTIFLCTEP HDKKEDLLEP QEQLPPPPLP PPVSQVDAAI GLLMPPLQTP VNLSVFCDHN YTVEDTMHQR KRIHQLEQQV EKLRKKLKTA QQRCRRQERQ LEKLKEVVHF QKEKDDVSER GYVILPNDYF EIVEVPA
Gene Category	Apoptosis

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 10/23/2025

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