DUSP13, 1-198aa Human, His tag, E.coli

DUSP13 (Dual specificity phosphatase 13) belongs to the protein-tyrosine phosphatase family. It cooperates with protein kinases to regulate cell proliferation and differentiation. DUSP13 is involved in the regulation of meiosis and/or differentiation of testicular germ cells during spermatogenesis. This protein exhibits intrinsic phosphatase activity towards both phospho-seryl/threonyl and -tyrosyl residues of myelin basic protein, with similar specific activities in vitro. Recombinant human DUSP13 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

0.5mg/ml (determined by Bradford assay)

• Chen H.-H., et al. (2004) J. Biol. Chem. 279:41404-41413
• Katagiri C, et al. (2011) Mol Cell Biochem. 352(1-2):155-62.

>, 95% by SDS - PAGE

MGSSHHHHHH SSGLVPRGSH MGSHMDSLQK QDLRRPKIHG AVQASPYQPP TLASLQRLLW VRQAATLNHI DEVWPSLFLG DAYAARDKSK LIQLGITHVV NAAAGKFQVD TGAKFYRGMS LEYYGIEADD NPFFDLSVYF LPVARYIRAA LSVPQGRVLV HCAMGVSRSA TLVLAFLMIC ENMTLVEAIQ TVQAHRNICP NSGFLRQLQV LDNRLGRETG RF