Comparison

TGFBRAP1, 601-860aa Human, His tag, E.coli

Item no. ARP-01-P2588-50
Manufacturer American Research Products
Amount 50 ug
Quantity options 10 ug 250 ug 50 ug
Category
Type Proteins Recombinant
Specific against other
Purity > 80% by SDS - PAGE
Sequence MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSKRLQ KEEYHTHLAV LYLEEVLLQR ASASGKGAEA TETQAKLRRL LQKSDLYRVH FLLERLQGAG LPMESAILHG KLGEHEKALH ILVHELQDFA AAEDYCLWCS EGRDPPHRQQ LFHTLLAIYL HAGPTAHELA VAAVDLLNRH ATEFDAAQVL QMLPDTWSVQ LLCPFLMGAM RDSIHARRTM QVALGLARSE NL
Citations Felts SJ, Owen BA, et al. (2000). J Biol Chem. 275(5):3305-12.Simmons AD, Musy MM, et al. (1999). Hum Mol Genet. 8(12):2155-64.
NCBI NP_004248
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Transforming growth factor, beta receptor associated protein 1, TRAP-1, TRAP1
Available
Description
TGFBRAP1 plays a role in the TGF-beta/activin signaling pathway. It associates with inactive heteromeric TGF-beta and activin receptor complexes, mainly through the type II receptor, and is released upon activation of signaling. It may recruit SMAD4 to the vicinity of the receptor complex and facilitate its interaction with receptor-regulated Smads, such as SMAD2. Recombinant human TGFBRAP1 protein, fused to His-tag at N-terminus, was expressed in E.coli.
Form
Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 10% glycerol
Storage
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Synonyms
Transforming growth factor, beta receptor associated protein 1, TRAP-1, TRAP1
Concentration
0.5 mg/ml (determined by Bradford assay)
NCBI
NP_004248
References
  • Felts SJ, Owen BA, et al. (2000). J Biol Chem. 275(5):3305-12.
  • Simmons AD, Musy MM, et al. (1999). Hum Mol Genet. 8(12):2155-64.
Antigen Recognized in Species
Human
Purity
>, 80% by SDS - PAGE
Molecular Weight
33 kDa (269aa)
Amino Acid Sequence
MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSKRLQ KEEYHTHLAV LYLEEVLLQR ASASGKGAEA TETQAKLRRL LQKSDLYRVH FLLERLQGAG LPMESAILHG KLGEHEKALH ILVHELQDFA AAEDYCLWCS EGRDPPHRQQ LFHTLLAIYL HAGPTAHELA VAAVDLLNRH ATEFDAAQVL QMLPDTWSVQ LLCPFLMGAM RDSIHARRTM QVALGLARSE NLIYTYDKMK LKGSSIQLSD KKLCQICQNP FCEPVFVRYP NGGLVHTHCA ASRHTNPSSS SPGTRT
Gene Category
Cancer

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 ug
Available: In stock
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