Comparison

GARS, 43-289aa, Human, His tag, E.coli

Item no. ARP-01-P2756-250
Manufacturer American Research Products
Amount 250 ug
Quantity options 10 ug 250 ug 50 ug
Category
Type Proteins Recombinant
Specific against other
Purity > 85% by SDS - PAGE
Sequence MGSSHHHHHH SSGLVPRGSH MGSPISLPAA ASRSSMDGAG AEEVLAPLRL AVRQQGDLVR KLKEDKAPQV DVDKAVAELK ARKRVLEAKE LALQPKDDIV DRAKMEDTLK RRFFYDQAFA IYGGVSGLYD FGPVGCALKN NIIQTWRQHF IQEEQILEID CTMLTPEPVL KTSGHVDKFA DFMVKDVKNG ECFRADHLLK AHLQKLMSDK KCSVEKKSEM ESVLAQLDNY GQ
Citations Guo R.-T., et al. (2009) J. Biol. Chem. 284:28968-28976Xie W., et al. (2007) Proc. Natl. Acad. Sci. U.S.A. 104:9976-9981
NCBI NP_002038
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Glycyl-tRNA synthetase, CMT2D, DSMAV, GlyRS, HMN5, SMAD1
Available
Description
GARS, also known as glycyl-tRNA synthetase, is one of the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids. This enzyme is an (alpha)2 dimer which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Recombinant human GARS protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Form
Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
Storage
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Synonyms
Glycyl-tRNA synthetase, CMT2D, DSMAV, GlyRS, HMN5, SMAD1
Concentration
0.5 mg/ml (determined by Bradford assay)
NCBI
NP_002038
References
  • Guo R.-T., et al. (2009) J. Biol. Chem. 284:28968-28976
  • Xie W., et al. (2007) Proc. Natl. Acad. Sci. U.S.A. 104:9976-9981
Antigen Recognized in Species
Human
Purity
>, 85% by SDS - PAGE
Molecular Weight
30.0 kDa (270aa), confirmed by MALDI-TOF
Amino Acid Sequence
MGSSHHHHHH SSGLVPRGSH MGSPISLPAA ASRSSMDGAG AEEVLAPLRL AVRQQGDLVR KLKEDKAPQV DVDKAVAELK ARKRVLEAKE LALQPKDDIV DRAKMEDTLK RRFFYDQAFA IYGGVSGLYD FGPVGCALKN NIIQTWRQHF IQEEQILEID CTMLTPEPVL KTSGHVDKFA DFMVKDVKNG ECFRADHLLK AHLQKLMSDK KCSVEKKSEM ESVLAQLDNY GQQELADLFV NYNVKSPITG NDLSPPVSFN LMFKTFIGPG
Gene Category
Epigenomics (Transcription &, Translation)

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 250 ug
Available: In stock
available

Delivery expected until 8/21/2025 

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