MIG (CXCL9), Mouse, Recombinant

MIG, a CXC chemokine, is produced by IFN-gamma times, stimulated monocytes, macrophages and endothelial cells. It signals through the CXCR3 receptor. MIG selectively chemo attracts Th1 lymphocytes, and also exerts other activities including inhibition of tumor growth, angiogenesis, and inhibition of colony formation of hematopoietic progenitors. Human MIG is active on murine cells. Recombinant murine MIG is a 12.2 kDa protein containing 105 amino acid residues, including the four highly conserved cysteine residues present in CXC chemokines.

Monokine Induced by Interferon-gamma, CXCL9

E. Coli

TLVIRNARCS CISTSRGTIH YKSLKDLKQF APSPNCNKTE IIATLKNGDQ TCLDPDSANV KKLMKEWEKK INQKKKQKRG KKHQKNMKNR KPKTPQSRRR SRKTT

Determined by its ability to chemoacttract human lymphocytes using a concentration range of 0.1-1.0 ng/ml.

Verified by N-terminal and Mass Spectrometry analyses (when applicable).