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Tau (Tau-441), human recombinant, Biotin labeled

Tau (Tau-441), human recombinant, Biotin labeled

Item no.	AS-56084
Manufacturer	AnaSpec
Amount	50 ug
Category	Neuroscience Molecular Targets for Neuroscience Targets for Rodent Neurosciences Aging & Neurological Disorders Protein Aggregation, Clearance & Misfolding Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Format	Liquid
Specific against	other
Host	E.coli
Conjugate/Tag	Biotin
Dry ice	Yes
Citations	1. Bulic B., Neuropharmacology. 59(2010):276-89. 2. Voss K., Mol. Neurodegen. 4(2009):1-12. 3. Rankin CA., Mol. Neurodegen. 2(2007):1-14. 4. Patterson KR., J. of Biol. Chem. 286(2011):23063-76. 5. Wang Y., Biochem. Soc. Trans. 38(2010):955-61. 6. Derisbourg M., Sci Rep. 5(2015):9659. 7. Stopschinski BE., J Biol Chem. 295(2020):2974-83. 8. Berrocal M., Biochim Biophys Acta. 1852(2015):1465-76. 9. Flach K., Biochim Biophys Acta. 1842(2014):1527-38. 10. Makrides V., J Biol Chem. 278(2003):33298-304.
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Recombinant Tau,Tau-441,Human Tau 441,MAPT,Tau-Biotin,Biotinylated Tau,Tau-441-biotin,Biotinylated Tau-441
Shipping Condition	Dry ice
Available
Manufacturer - Type	Catalog recombinant
Manufacturer - Category	Catalog Recombinant Proteins / Catalog Recombinant / Proteins
Manufacturer - Targets	Tau
Shipping Temperature	Dry Ice
Storage Conditions	Store at -80°C. Avoid repeated freeze-thaw cycles.
Molecular Weight	71.8 kDa (higher apparent mass in SDS-PAGE)
Manufacturer - Research Area	Neuroscience / Alzheimer's Disease
Description	Microtubule associated protein (Tau) is found predominantly in the central neural system and its major function is to promote assembly and to stabilize neuronal microtubules. Six isoforms of Tau were identified in humans that are differentiated by the exclusion or inclusion of exons 2, 3, and 10. Tau-441 is the longest of Tau isoforms that consists of 441 amino acids with a molecular mass of 45.8 kDa. Tau441-Biotin conjugates have been reported in applications such as Tau species identification and different binding assays. - The recombinant human Tau (Tau-441) (GenBank Accession # AAC04279.1) was expressed and purified from E. coli and conjugated with biotin.
Purification Method	Purified
Concentration	1 mg/ml
Storage Buffer	10 mM sodium phosphate buffer (pH=7.4)
Manufacturer - Specificity	full length human Tau-441 (2N4R isoform) protein
Post Synthesis Coupling	No
Usage	Research use
Nacres Code	NA.27
UNSPSC	12352202
GTIN	5400535193898

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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AS-56084-safety-datasheet.pdf