Comparison

Biotinylated Human B7-H3 (4Ig) / B7-H3b Protein, Fc,Avitag™ (MALS verified) European Partner

Item no. B7B-H82F5-200ug
Manufacturer ACROBiosystems
Amount 100 ug x 2
Quantity options 100 ug x 2 25 ug
Category
Type Proteins Recombinant
Format Solid
Specific against Human (Homo sapiens)
Host HEK293
Conjugate/Tag Biotin, Avi, Fc
Purity 95%
Citations (1) Chapoval AI., et al. 2001, Nat Immunol., 2(3), 269-74. (2) Steinberger P., et al. 2004, J Immunol., 172(4), 2352-9. (3) Sun M., et al. 2002, J Immunol., 168(12), 6294-7.
NCBI NP_001019907.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias 4Ig-B7-H3,B7-H3,CD276,PSEC0249,UNQ309/PRO352,B7 homolog 3
Shipping Condition Room temperature
Available
Manufacturer - Category
Protein / MABSol® Biotin Labeled Proteins
Manufacturer - Conjugate / Tag
C-Fc & C-Avi, Biotin-labeled
Shipping Temperature
RT
Storage Conditions
-20°C
Molecular Weight
74.9 kDa
Manufacturer - Format
Powder
Description
Biotinylated Human B7-H3 (4Ig), Fc, Avitag (B7B-H82F5) is expressed from human 293 cells (HEK293). It contains AA Gly 27 - Thr 461 (Accession # Q5ZPR3-1).
Background
Human B7 homolog 3 (B7-H3) is a member of the B7 family of immune proteins that provide signals for the regulation of immune responses. Other family members include B7-1, B7-2, B7-H1/PD-L1, B7-H2, and PD-L2. B7 family proteins are type I transmembrane immunoglobulin (Ig) superfamily members that contain extracellular Ig V‑like and Ig C‑like domains with a short cytoplasmic tail. Termed 4IgB7-H3 or B7-H3b, this molecule has two additional Ig-like domains (one V‑type and one C‑type) and shows a ubiquituous expression pattern.
Molecule
B7-H3 (4Ig)
Exp Region
Gly 27 - Thr 461
Characteristics
This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 74.9 kDa. The protein migrates as 90-115 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
1.0 EU per μg
Buffer
Tris with Glycine, Arginine and NaCl, pH 7.5
Stability
● -20°C to -70°C for 12 months in lyophilized state;
● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant
trehalose

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug x 2
Available: In stock
available

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