Manufacturer |
Biomatik
|
Category |
|
Type |
Proteins Recombinant |
Specific against |
Human |
Amount |
100ug |
Item no. |
BM-RPC20717-100ug |
eClass 6.1 |
34160400 |
eClass 9.0 |
42020190 |
Available |
|
Gene Name |
CLDN6 |
Alternative Names |
Skullin |
Uniprot |
P56747 |
Source |
in vitro E.coli expression system |
Expression Region |
1-82aa |
AA Sequence |
MASAGMQILGVVLTLLGWVNGLVSCALPMWKVTAF IGNSIVVAQVVWEGLWMSCVVQSTGQMQCKVYDSL LALPQDLQAARA |
Sequence Info |
Partial |
Tag Info |
N-terminal 6xHis-SUMO-tagged |
Theoretical MW |
24.8 kDa |
Purity |
>90% as determined by SDS-PAGE. |
Storage Buffer |
Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0. |
Endotoxin Level |
Not tested |
Biological Activity |
Not tested |
Shipping Condition |
Ice packs |
Storage |
Short term: -20CC; Long term: -80CC. Minimize freeze and thaw cycles. |
Expiry Date |
1 year |
Restriction |
For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals. |
Relevance |
Plays a major role in tight junction-specific obliteration of the intercellular space (By similarity). May act as a coreceptor for HCV entry into hepatic cells. |
Function |
Plays a major role in tight junction-specific obliteration of the intercellular space. |
Subcellular location |
Cell junction, tight junction, Cell membrane, Multi-pass membrane protein |
Protein Families |
Claudin family |
Tissue Specificity |
Expressed in the liver, in peripheral blood mononuclear cells and hepatocarcinoma cell lines. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.