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Recombinant Horse Interleukin-1 beta protein (IL1B) (Active)

Recombinant Horse Interleukin-1 beta protein (IL1B) (Active)

Manufacturer	Biomatik
Category	Neuroscience Neuroinflammation Metabolism Cholesterol & Lipid Metabolism Peptides & Proteins Recombinant Proteins Cell Biology Cell Movement Cell Adhesion Cell Culture Cytokines
Type	Proteins Recombinant
Specific against	Equine
Amount	1mg
Item no.	BM-RPC26544-1mg
Targets	IL1B
eClass 6.1	34160400
eClass 9.0	42020190
Available
Gene Name	IL1B
Alternative Names	Interleukin-1 beta Short name: IL-1 beta
Uniprot	Q28386
Source	E.coli
Expression Region	116-268aa
AA Sequence	AAMHSVNCRL RDIYHKSLVL SGACELQAVH LN GENTNQQV VFCMSFVQGE EETDKIPVAL GLKE KNLYLS CGMKDGKPTL QLETVDPNTY PKRKME KRFV FNKMEIKGNV EFESAMYPNW YISTSQAE KS PVFLGNTRGG RDITDFIMEI TSA
Sequence Info	Full Length of Mature Protein
Tag Info	Tag-Free
Theoretical MW	17.3 kDa
Purity	>95% as determined by SDS-PAGE and HPLC.
Storage Buffer	Lyophilized from a 0.2 um filtered PBS, pH 7.4, 0.1 % Tween-80
Endotoxin Level	Less than 1.0 EU/ug as determined by LAL method.
Biological Activity	The ED50 as determined by a cell proliferation assay using murine D10S cells is less than 20 pg/ml, corresponding to a specific activity of ? 5.0 x 107 IU/mg.
Shipping Condition	Ice packs
Storage	Short term: -20CC; Long term: -80CC. Minimize freeze and thaw cycles.
Expiry Date	1 year
Restriction	For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.
Relevance	Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production.
Function	Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production.
Subcellular location	Cytoplasm, cytosol, Lysosome, Secreted, exosome, Cytoplasmic vesicle, autophagosome, Secreted
Protein Families	IL-1 family

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1mg

available

Delivery expected until 6/27/2024