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Mouse BTLA Protein, Fc Tag (MALS verified)

Mouse BTLA Protein, Fc Tag (MALS verified)

Item no.	BTA-M5253-1mg
Manufacturer	ACROBiosystems
Amount	1 mg
Quantity options	100 ug 1 mg
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Solid
Specific against	Mouse (Murine, Mus musculus)
Host	HEK293
Conjugate/Tag	Unconjugated, Fc
Purity	95%
Citations	(1) Watanabe N., et al., 2003, Nat. Immunol. 4:670-679. (2) Gavrieli M., et al., 2003, Biochem. Biophys. Res. Commun. 312:1236-1243. (3) Sedy J.R., et al., 2005, Nat. Immunol. 6:90-98.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	BTLA,CD272
Shipping Condition	Room temperature
Available
Manufacturer - Category	Protein / Immune Checkpoint Proteins
Manufacturer - Conjugate / Tag	C-Fc, Unconjugated
Shipping Temperature	RT
Storage Conditions	-20°C
Molecular Weight	42.8 kDa
Manufacturer - Format	Powder
Description	Mouse BTLA, Fc Tag (BTA-M5253) is expressed from human 293 cells (HEK293). It contains AA Glu 30 - Gly 176 (Accession # Q32MV9).
Background	B- and T-lymphocyte attenuator (BTLA) is also known as B- and T-lymphocyte-associated protein, CD antigen CD272. BTLA contains one Ig-like V-type (immunoglobulin-like) domain. As a lymphocyte inhibitory receptor, BTLA / CD272 inhibits lymphocytes during immune response. BTLA / CD272 can interact with tyrosine phosphatases PTPN6/SHP-1 and PTPN11/SHP-2, and interact with TNFRSF14/HVEM.
Molecule	BTLA
Exp Region	Glu 30 - Gly 176
Characteristics	This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 42.8 kDa. The protein migrates as 55-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	Tris with Glycine, Arginine and NaCl, pH 7.5
Stability	● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant	trehalose

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BTA-M5253-1mg-datasheet.pdf

BTA-M5253-1mg-safety-datasheet.pdf