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Human CCR5 Protein, Flag,His Tag (Detergent)

Human CCR5 Protein, Flag,His Tag (Detergent)

Item no.	CC5-H52D1-100ug
Manufacturer	ACROBiosystems
Amount	100 ug
Quantity options	100 ug 20 ug 500 ug
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Liquid
Specific against	Human (Homo sapiens)
Host	HEK293
Conjugate/Tag	Unconjugated, FLAG
Purity	85%
Dry ice	Yes
Citations	(1) M Samson. et al., 1996, Biochemistry 19;35(11):3362-7. (2) C Blanpain. et al., 2001, J Biol Chem 29;276(26):23795-804. (3) Einat Schnur. et al., 2001, J Mol Biol 29;410(5):778-97.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	CCR5,CMKBR5,CD195,CC-CKR-5,CHEMR13
Shipping Condition	Dry ice
Available
Manufacturer - Category	Protein
Manufacturer - Conjugate / Tag	N-Flag & C-10xHis, Unconjugated
Shipping Temperature	Dry ice
Storage Conditions	-70°C
Molecular Weight	46.0 kDa
Manufacturer - Format	Liquid
Description	Receptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation.5 Publications (Microbial infection) Acts as a coreceptor (CD4 being the primary receptor) of human immunodeficiency virus-1/HIV-1.
Background	Receptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation.5 Publications (Microbial infection) Acts as a coreceptor (CD4 being the primary receptor) of human immunodeficiency virus-1/HIV-1.
Molecule	CCR5
Exp Region	Asp 2 - Arg 223 & Glu 227 - Arg 319
Characteristics	This protein carries a flag tag at the N-terminus and a polyhistidine tag at the C-terminus. The protein has a calculated MW of 46.0 kDa. The protein migrates as 40-43 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).
Endotoxin	1.0 EU per μg
Buffer	50 mM HEPES, 150 mM NaCl, DDM, CHS, pH7.5
Stability	● The product MUST be stored at -70°C or lower upon receipt ● -70°C for 3 months under sterile conditions.
Protectant	glycerol

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

CC5-H52D1-100ug-datasheet.pdf

CC5-H52D1-100ug-safety-datasheet.pdf