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FITC-Compatible Human CD19 Protein (CD1-HM119F)

FITC-Compatible Human CD19 Protein (CD1-HM119F)

Item no.	CD1-HM119F-500UG
Manufacturer	KactusBio
Amount	500 ug
Quantity options	100 ug 500 ug
Category	Oncology By Cell Type Hematology Leukemia Lymphoma Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Liquid
Specific against	Human (Homo sapiens)
Host	HEK293
Conjugate/Tag	HIS
Purity	> 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
Formula	Supplied as 0.22 μm filtered solution in PBS (pH 7.4).
Dry ice	Yes
Sequence	Pro20-Lys291
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	CD19, B4, CVID3, Leu-12, MGC12802
Available
Manufacturer - Type	Recombinant Protein
Manufacturer - Targets	FITC-Compatible CD19
Manufacturer - Conjugate / Tag	C-His
Shipping Temperature	Shipped with dry ice.
Storage Conditions	Valid for 12 months from date of receipt when stored at -80°C; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Molecular Weight	The protein has a predicted MW of 60.1 kDa. Due to glycosylation, the protein migrates to 68-72 kDa based on Bis-Tris PAGE result.
Description	FITC-Compatible Human CD19 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Pro20-Lys291.
Background	CD19 is a B-lineage-specific transmembrane glycoprotein, the expression of which is maintained on more than 95% B-cell malignancies. This strict lineage restriction makes CD19 an ideal target for immune therapies using chimeric antigen receptors (CARs). T cells engineered to express a chimeric antigen receptor (CAR) against CD19 have recently been FDA approved for the treatment of relapsed or refractory large B-cell lymphoma. Despite the success and curative potential of CD19 CAR T cells, several reports describing disease relapse due to antigen loss are now emerging.
Endotoxin	Less than 1 EU per μg by the LAL method.
Formulation	Supplied as 0.22 μm filtered solution in PBS (pH 7.4).
Biotinylated	no

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

CD1-HM119F-500UG-datasheet.pdf

CD1-HM119F-500UG-safety-datasheet.pdf