Comparison

FITC-Labeled Human CD4 Protein, Fc Tag European Partner

Item no. CD4-HF255-200ug
Manufacturer ACROBiosystems
Amount 200 ug
Quantity options 200 ug 25 ug
Category
Type Proteins Recombinant
Format Solid
Specific against Human (Homo sapiens)
Host HEK293
Conjugate/Tag FITC, Fc
Purity 95%
Citations (1) Brady RL, et al., 1993, Science 260 (5110): 979-83. (2) Zeitlmann, L., et al., 2001, J. Biol. Chem. (United States) 276 (12): 9123-32. (3) Rudd CE, et al., 2010, J. Immunol. 185 (5): 2645-9. (4) Rudd CE, et al., 1988, Proc. Natl. Acad. Sci. U.S.A. 85 (14): 5190-4. (5) Gorska MM, et al., 2004, J. Exp. Med. 199 (3): 369-79.
NCBI AAH25782
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias CD4,CD4mut,LEU3
Shipping Condition Room temperature
Available
Manufacturer - Category
Protein
Manufacturer - Conjugate / Tag
C-Fc, FITC Labeled
Shipping Temperature
RT
Storage Conditions
-20°C, avoid light
Molecular Weight
67.7 kDa
Manufacturer - Format
Powder
Description
FITC-Labeled Human CD4, Fc Tag (CD4-HF255) is expressed from human 293 cells (HEK293). It contains AA Lys 26 - Pro 396 (Accession # P01730). It is the FITC labeled form of Human CD4, Fc Tag (CD4-H5259).
Background
T-cell surface glycoprotein CD4 is also known as T-cell surface antigen T4/Leu-3. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is accessory protein for MHC class-II antigen/T-cell receptor interaction. CD4 induces the aggregation of lipid rafts. CD4 is a primary receptor used by HIV-1 to gain entry into host T cells. HIV infection leads to a progressive reduction of the number of T cells possessing CD4 receptors. Therefore, medical professionals refer to the CD4 count to decide when to begin treatment for HIV-infected patients.
Molecule
CD4
Exp Region
Lys 26 - Pro 396
Characteristics
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 67.7 kDa. The protein migrates as 67-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
1.0 EU per μg
Buffer
PBS, pH7.4
Stability
● -20°C to -70°C for 12 months in lyophilized state
● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant
trehalose

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 200 ug
Available: In stock
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