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Biotinylated Human CD47 Protein (Primary Amine Labeling) (CD7-HM247B)

Biotinylated Human CD47 Protein (Primary Amine Labeling) (CD7-HM247B)

Item no.	CD7-HM247B-500UG
Manufacturer	KactusBio
Amount	500 ug
Quantity options	100 ug 500 ug
Category	Oncology Neuroscience Targets for Rodent Neurosciences By Cell Type Hematology Leukemia Lymphoma Peptides & Proteins Recombinant Proteins Cell Biology Cell Movement Cell Adhesion
Type	Proteins Recombinant
Format	Liquid
Specific against	Human (Homo sapiens)
Host	HEK293
Conjugate/Tag	C-hFc
Purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Formula	Supplied as 0.22μm filtered solution in PBS (pH 7.4).
Sequence	Gln19-Pro139
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	CD47 glycoprotein, CD47 molecule, CD47, IAP, OA3, MER6
Available
Shipping Temperature	Shipped with blue ice
Storage Conditions	Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please avoid repeated freeze-thaw cycles.
Molecular Weight	The protein has a predicted MW of 40.5 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result.
Description	Recombinant Biotinylated Human CD47 Protein (Primary Amine Labeling) is expressed from HEK293 with hFc tag at the C-terminal.It contains Gln19-Pro139.
Background	CD47 (Cluster of Differentiation 47) also known as integrin associated protein (IAP) is a transmembrane protein that in humans is encoded by the CD47 gene. CD47 belongs to the immunoglobulin superfamily and partners with membrane integrins and also binds the ligands thrombospondin-1 (TSP-1) and signal-regulatory protein alpha (SIRPα).CD-47 acts as a don't eat me signal to macrophages of the immune system which has made it a potential therapeutic target in some cancers.
Endotoxin	Less than 1EU per μg by the LAL method.
Formulation	Supplied as 0.22μm filtered solution in PBS (pH 7.4).
Biotinylated	yes

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

CD7-HM247B-500UG-datasheet.pdf

CD7-HM247B-500UG-safety-datasheet.pdf