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Rabbit CD3E&CD3D Heterodimer Protein, Llama Fc&Llama Fc, low endotoxin (MALS verified)

Rabbit CD3E&CD3D Heterodimer Protein, Llama Fc&Llama Fc, low endotoxin (MALS verified)

Item no.	CDD-R5259-1mg
Manufacturer	ACROBiosystems
Amount	1 mg
Quantity options	100 ug 1 mg
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Solid
Specific against	Rabbit (Oryctolagus cuniculus)
Host	HEK293
Conjugate/Tag	Unconjugated
Purity	95%
Citations	(1) Gold DP, et al., 1986, Nature 321 (6068): 431-4. (2) Clevers HC, et al., 1988, Proc. Natl. Acad. Sci. U.S.A. 85 (21): 8156-60. (3) Gil J, et al., 2011, J Clin Invest, 121(10):3872-6. (4) Lu X, et al.,2011, Hematology, 16(3):185-9.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	CD3E & CD3D,CD3 delta & CD3 epsilon,CD3 delta / epsilon
Shipping Condition	Room temperature
Available
Manufacturer - Category	Protein
Manufacturer - Conjugate / Tag	C-LlamaFc(LlamaIgG2b) \| C-LlamaFc(LlamaIgG2b), Unconjugated
Shipping Temperature	RT
Storage Conditions	-20°C
Molecular Weight	42.4 kDa (CD3E) & 40.8 kDa (CD3D)
Manufacturer - Format	Powder
Description	T-cell surface glycoprotein CD3 delta & CD3 epsilon chain, also known as CD3D & CD3E or CD3D&CD3E respectively, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon(CD3E) , CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.
Background	T-cell surface glycoprotein CD3 delta & CD3 epsilon chain, also known as CD3D & CD3E or CD3D&CD3E respectively, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon(CD3E) , CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.
Molecule	CD3E & CD3D
Exp Region	Gln 22 - Thr 120 (CD3E) & Thr 22 - Ser 107 (CD3D)
Characteristics	Rabbit CD3E&CD3D Heterodimer Protein, Llama Fc&Llama Fc is produced by co-expression of CD3E and CD3D, has a calculated MW of 42.4 kDa (CD3E) and 40.8 kDa (CD3D). Subunit CD3E is fused with a llama IgG2b Fc tag at the C-terminus and subunit CD3D is fused with a llama IgG2b Fc tag at the C-terminus. The reducing (R) protein migrates as 50 kDa and 60 kDa due to glycosylation.
Endotoxin	0.01 EU per μg
Buffer	PBS, pH7.4
Stability	● -20°C to -70°C for 12 months in lyophilized state ● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant	trehalose

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

CDD-R5259-1mg-datasheet.pdf

CDD-R5259-1mg-safety-datasheet.pdf