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Human CD30 Ligand / TNFSF8 Protein, Mouse IgG2a Fc Tag, low endotoxin

Human CD30 Ligand / TNFSF8 Protein, Mouse IgG2a Fc Tag, low endotoxin

Item no.	CDL-H525b-100ug
Manufacturer	ACROBiosystems
Amount	100 ug
Quantity options	100 ug 250 ug x 4
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Solid
Specific against	Human (Homo sapiens)
Host	HEK293
Isotype	IgG2a
Conjugate/Tag	Unconjugated, N-mFc
Purity	95%
Citations	(1) Marin ND., et al. 2017, Tuberculosis (Edinb)., 102, 8-15. (2) Kennedy MK., et al. 2006, Immunology., 118(2), 143-52. (3) Horie R., et al. 1998, Semin Immunol., 10(6), 457-70.
NCBI	NP_001235.1
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	CD30-L,CD153,TNFSF8,CD30L,CD30LG,CD153 antigen,CD30 antigen ligand,CD30 Ligand
Shipping Condition	Room temperature
Available
Manufacturer - Category	Protein
Manufacturer - Conjugate / Tag	N-mFc(mIgG2a), Unconjugated
Shipping Temperature	RT
Storage Conditions	-20°C
Molecular Weight	46.5 kDa
Manufacturer - Format	Powder
Description	CD30 ligand (CD30L) and CD30 are interacting cellsurface glycoproteins that are members of the tumour necrosis factor (TNF) and tumour necrosis factor receptor (TNFR) superfamilies. In humans, CD30L is expressed at high levels on activated T cells. There is conflicting evidence with regard to cell surface expression of CD30L on primary human B cells. An initial report of constitutive CD30L expression on peripheral blood B cells33 has not been substantiated.
Background	CD30 ligand (CD30L) and CD30 are interacting cellsurface glycoproteins that are members of the tumour necrosis factor (TNF) and tumour necrosis factor receptor (TNFR) superfamilies. In humans, CD30L is expressed at high levels on activated T cells. There is conflicting evidence with regard to cell surface expression of CD30L on primary human B cells. An initial report of constitutive CD30L expression on peripheral blood B cells33 has not been substantiated.
Molecule	CD30 ligand
Exp Region	Gln 63 - Asp 234
Characteristics	This protein carries a mouse IgG2a Fc tag at the N-terminus. The protein has a calculated MW of 46.5 kDa. The protein migrates as 55-65 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	0.01 EU per μg
Buffer	Tris with Glycine, Arginine and NaCl, pH7.5
Stability	● -20°C to -70°C for 12 months in lyophilized state ● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant	trehalose

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

CDL-H525b-100ug-datasheet.pdf

CDL-H525b-100ug-safety-datasheet.pdf