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Biotinylated Human CEACAM-1 / CD66a Protein, Avitag™,His Tag European Partner

Item no. CE1-H82E5-200ug
Manufacturer ACROBiosystems
Amount 200 ug
Quantity options 200 ug 25 ug
Category
Type Proteins Recombinant
Format Solid
Specific against Human (Homo sapiens)
Host HEK293
Conjugate/Tag Biotin, HIS, Avi
Purity 95%
Citations (1) Kuroki M., et al., 1991, Biochem. Biophys. Res. Commun. 176:578-585. (2) Watt S.M., et al., 1994, Blood 84:200-210. (3) Chen R., et al., 2009, J. Proteome Res. 8:651-661. (4) Hoek KS., et al., 2008, Pigment Cell Melanoma Res. 21 (6): 665-76.
NCBI NP_001703.2
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias CEACAM1,CD66a,BGP,BGP1,BGPI
Shipping Condition Room temperature
Available
Manufacturer - Category
Protein / MABSol® Biotin Labeled Proteins
Manufacturer - Conjugate / Tag
C-Avi & C-6xHis, Biotin-labeled
Shipping Temperature
RT
Storage Conditions
-20°C
Molecular Weight
45.9 kDa
Manufacturer - Format
Powder
Description
Biotinylated Human CEACAM-1, Avitag, His Tag (CE1-H82E5) is expressed from human 293 cells (HEK293). It contains AA Gln 35 - Gly 428 (Accession # P13688-1).
Background
Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) is also known as Biliary glycoprotein 1 (BGP1), CD66a, which belongs to the immunoglobulin superfamily or CEA family. CEACAM1 /CD66a contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CEACAM1 /CD66a was described as an adhesion molecule mediating cell adhesion via both homophilic and heterophilic manners, and was detected on leukocytes, epithelia, and endothelia. Studies have revealed that CEACAM1 / BGP-1 performs actions in multiple cellular processes including tissue differentiation, angiogenesis, apoptosis, metastasis, as well as the modulation of innate and adaptive immune responses.
Molecule
CEACAM-1
Exp Region
Gln 35 - Gly 428
Characteristics
This protein carries an Avi tag (Avitag™) at the C-terminus, followed by a polyhistidine tag. The protein has a calculated MW of 45.9 kDa. The protein migrates as 66-115 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
1.0 EU per μg
Buffer
PBS, pH 7.4
Stability
● -20°C to -70°C for 12 months in lyophilized state;
● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant
trehalose

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 200 ug
Available: In stock
available

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