Comparison

LCMV Glycoprotein C (R262A) Protein, His Tag European Partner

Item no. CLN-L52H2-100ug
Manufacturer ACROBiosystems
Amount 100 ug
Quantity options 100 ug 1 mg
Category
Type Proteins
Format Solid
Specific against Virus
Host HEK293
Conjugate/Tag Unconjugated, HIS
Purity 95%
NCBI AJ297484.1 (R262A)
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Glycoprotein, g Protein
Shipping condition Room temperature
Available
Specificity LCMV
Manufacturer - Category
Protein
Manufacturer - Conjugate / Tag
C-10×His, Unconjugated
Manufacturer - Species
LCMV
Shipping Temperature
RT
Storage Conditions
-20°C
Molecular Weight
48.6 kDa
Description
LCMV Glycoprotein C (R262A) Protein, His Tag (CLN-L52H2) is expressed from human 293 cells (HEK293). It contains AA Met 59 - Asp 438 (Accession # AJ297484.1 (R262A)).
Background
Lymphocytic choriomeningitis virus (LCMV) is a spherical enveloped virus with an RNA genome consisting of two negative single-stranded RNA segments, the large (L) strand and the small (S) strand. The L strand encodes the virus polymerase (L) and a small zinc finger motif protein (Z); the smaller (S) segment encodes the two main structural proteins: virus nucleoprotein (NP) and glycoprotein (GP) precursor (GPC). The GP of LCMV serves as virus attachment protein to its receptor on host cells and is a key determinant for cell tropism, pathogenesis, and epidemiology of the virus. The GP undergoes post-translational cleavage and results in the synthesis of two mature virion glycoproteins, GP-1 (40 to 46 kDa) and GP-2 (35 kDa). The spikes present on the virion envelope are dictated by tetramer formation of GP-1 and GP-2. The peripheral GP-1 is implicated in receptor binding, and the transmembrane GP-2 is structurally similar to the fusion active membrane proximal portions of the glycoproteins of other enveloped viruses.
Molecule
Glycoprotein C/GP-C (LCMV)
Exp Region
Met 59 - Asp 438
Characteristics
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 48.6 kDa. The protein migrates as 66-70 kDa and 80-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
1.0 EU per μg
Buffer
PBS, 0.5 M Arginine, pH7.3
Stability
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant
trehalose

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
available

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