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Human CNTF R alpha Protein, His Tag

Human CNTF R alpha Protein, His Tag

Item no.	CNR-H5225-100ug
Manufacturer	ACROBiosystems
Amount	100 ug
Quantity options	100 ug 1 mg
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Solid
Specific against	Human (Homo sapiens)
Host	HEK293
Conjugate/Tag	Unconjugated, HIS
Purity	95%
Citations	(1) Davis S., et al., 1991, Science 253 (5015): 59-63. (2) Sleeman MW., et al., 2000, Pharm Acta Helv 74 (2-3): 265-72.
NCBI	AAH01492
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	CNTFR,CNTF R alpha
Shipping condition	Room temperature
Available
Manufacturer - Category	Protein / Bio-Markers & CD Antigens
Manufacturer - Conjugate / Tag	C-11×His, Unconjugated
Shipping Temperature	RT
Storage Conditions	-20°C
Molecular Weight	37.6 kDa
Description	Human CNTF R alpha, His Tag (CNR-H5225) is expressed from human 293 cells (HEK293). It contains AA Gln 23 - Pro 346 (Accession # AAH01492).
Background	Ciliary neurotrophic factor receptor subunit alpha (CNTFR or CNTFR-alpha) belongs to the type I cytokine receptor family and type 3 subfamily. CNTFR contains two fibronectin type-III domains and one Ig-like C2-type (immunoglobulin-like) domain. This receptor and its cognate ligand support the survival of neurons. This receptor is most closely related to the interleukin-6 receptor. This receptor possesses an unusual attachment to the cell membrane through a glycophosphatidylinositol linkage.
Molecule	CNTF R alpha
Exp Region	Gln 23 - Pro 346
Characteristics	This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 37.6 kDa. The protein migrates as 45-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	PBS, pH7.4
Stability	-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant	trehalose

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

CNR-H5225-100ug-datasheet.pdf

CNR-H5225-100ug-safety-datasheet.pdf