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PDGF-BB

PDGF-BB

Item no.	E21-199
Manufacturer	Enogene
Amount	10 ug
Category	Oncology By Cell Type Blastoma Carcinoma Glioma Sarcoma Peptides & Proteins Recombinant Proteins
Type	Proteins
Format	Lyophilized
Specific against	Human (Homo sapiens)
Host	E.coli
Purity	Greater than 95% as determined by reducing SDS-PAGE.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Platelet-Derived Growth Factor Subunit B,PDGF Subunit B,PDGF-2,Platelet-Derived Growth Factor B Chain,Platelet-Derived Growth Factor Beta Polypeptide,Proto-Oncogene c-Sis,Becaplermin,PDGFB,PDGF2,SIS
Shipping Condition	Room temperature
Available
Shipping Temperature	The product is shipped at ambient temperature. Ambient
Storage Conditions	Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Background	Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma.Binding of PDGFB to its receptor elicits a variety of cellular responses. In addition, PDGFB is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound.
Description	Recombinant Human Platelet-Derived Growth Factor BB is produced by our E.coli expression system and the target gene encoding Ser82-Thr190 is expressed.
Endotoxin	Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
Formulation Description	Lyophilized from a 0.2 μm filtered solution of 4mM HCl.
Reconstitution	Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 ug

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Delivery expected until 2/26/2026

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