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Recombinant Human PDGF-BB Protein (His Tag)

Recombinant Human PDGF-BB Protein (His Tag)

Item no.	ELS-PKSH030442-50ug
Manufacturer	Elabscience
Amount	50 ug
Quantity options	200 ug 50 ug 1 mg
Category	Oncology By Cell Type Blastoma Carcinoma Glioma Sarcoma Peptides & Proteins Recombinant Proteins
Type	Proteins
Format	Lyophilized Powder
Applications	ELISA
Specific against	Human (Homo sapiens)
Host	Yeast
Conjugate/Tag	HIS
Purity	> 95 % as determined by reducing SDS-PAGE.
Sequence	Ser82-Thr190
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Becaplermin, PDGF Subunit B, PDGF-2, PDGF2, PDGFB, Platelet-Derived Growth Factor B Chain, Platelet-Derived Growth Factor Beta Polypeptide, Platelet-Derived Growth Factor Subunit B, Proto-Oncogene c-Sis, SIS
Similar products	PDGFB, PDGF2, SIS, PDGF-2, Becaplermin, Platelet-Derived Growth Factor Subunit B, PDGF Subunit B, Platelet-Derived Growth Factor B Chain, Platelet-Derived Growth Factor Beta Polypeptide, Proto-Oncogene c-Sis
Shipping Condition	Cool pack
Available
Manufacturer - Category	Recombinant Proteins / Others
Manufacturer - Conjugate / Tag	N-His
Shipping Temperature	This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight	14.3 kDa
Manufacturer - Research Areas	Signal Transduction, Cardiovascular, Cancer, Developmental Biology, metabolism,
Background	Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma.Binding of PDGFB to its receptor elicits a variety of cellular responses. In addition, PDGFB is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound.
Endotoxin	Please contact us for more information.
Reconstitution	Please refer to the printed manual for detailed information.
Formulation	Lyophilized from sterile PBS, 25 % Glycerol, pH 7.4 Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Activity	Immobilized human PDGFB at 10μg/mL (100μL/well) can bind human PDGFRβ-Fch, the EC50 of human PDGFRβ-Fch is 0.05-0.2 μg/mL.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

ELS-PKSH030442-50ug-datasheet.pdf

ELS-PKSH030442-50ug-safety-datasheet.pdf