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Recombinant Human Transferrin Receptor/TFRC Protein (His Tag)

Recombinant Human Transferrin Receptor/TFRC Protein (His Tag)

Item no.	ELS-PKSH031302-50ug
Manufacturer	Elabscience
Amount	50 ug
Quantity options	100 ug 50 ug 1 mg
Category	Oncology Neuroscience Targets for Rodent Neurosciences By Cell Type Hematology Leukemia Peptides & Proteins Recombinant Proteins
Type	Proteins
Format	Lyophilized Powder
Applications	ELISA
Specific against	Human (Homo sapiens)
Host	HEK293 cells
Conjugate/Tag	HIS
Purity	> 85 % as determined by reducing SDS-PAGE.
Sequence	Cys 89-Phe 760
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	CD71, T9, TFR, TR, TRFR, TfR, Transferrin receptor protein 1, Trfr, p90
Similar products	CD71, TR, TFR, p90, TRFR, T9, Transferrin receptor protein 1, TfR, Trfr
Shipping Condition	Cool pack
Available
Manufacturer - Category	Recombinant Proteins / Others
Manufacturer - Conjugate / Tag	N-His
Shipping Temperature	This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight	77.4 kDa
Manufacturer - Research Areas	Cardiovascular, Cancer, immunology, metabolism, Stem cells
Background	Transferrin receptor protein 1, also known as transferrin receptor, Trfr, p90, CD71 and TFRC, is a single-pass type II membrane protein which belongs to thepeptidase M28 family and M28B subfamily. TFRC / CD71 is a membrane-bound protein expressed in larger amounts in proliferating. The specific expression of TFRC can represent a diagnostic tool or a therapeutic target in solid tumours expressing this antigen. Transferrin receptor is necessary for development of erythrocytes and the nervous system. TFRC / CD71 is regulated by cellular iron levels through binding of the iron regulatory proteins, IRP1 and IRP2, to iron-responsive elements in the 3'-UTR. Up-regulated upon mitogenic stimulation. TFRC / CD71 represents a marker of malignant transformation in the pancreas that could be applied as potential diagnostic and therapeutic target.
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method.
Reconstitution	Please refer to the printed manual for detailed information.
Formulation	Lyophilized from sterile PBS, pH 7.4 Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Activity	Immobilized human CD71 at 10 μg/ml (100 μl/well) can bind human Transferrin. The EC50 of human Transferrin is 5. 6 ng/mL.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

ELS-PKSH031302-50ug-datasheet.pdf

ELS-PKSH031302-50ug-safety-datasheet.pdf