Comparison

Recombinant Human 4-1BBL/TNFSF9 Protein (His Tag)

Item no. ELS-PKSH032023-50ug
Manufacturer Elabscience
Amount 50 ug
Quantity options 10 ug 50 ug 100 ug 20 ug
Category
Type Proteins
Format Lyophilized Powder
Applications Cell Culture
Specific against Human (Homo sapiens)
Host E.coli
Conjugate/Tag HIS
Purity > 95 % as determined by reducing SDS-PAGE.
Sequence Arg71-Asp 140
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias 4-1BB ligand, 4-1BBL, TNFSF9, Tumor necrosis factor ligand superfamily member 9
Similar products 4-1BBL, TNFSF9, Tumor necrosis factor ligand superfamily member 9, 4-1BB ligand
Shipping Condition Cool pack
Available
Manufacturer - Category
Recombinant Proteins / Immune Checkpoint Proteins
Manufacturer - Conjugate / Tag
C-His
Shipping Temperature
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
20.4 kDa
Observed Molecular Weight
20 kDa
Manufacturer - Research Areas
Cancer, immunology
Background
Tumor necrosis factor ligand superfamily member 9(4-1BBL) is single-pass type II membrane protein which is a member of the the tumor necrosis factor family. 4-1BBL is a 254 amino acids cytokine that is expressed in brain; placenta; lung; skeletal muscle and kidney. TNFSF9 has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine may have a role in activation-induced cell death (AICD) and cognate interactions between T-cells and B-cells/macrophages. It has also been shown to be required for the optimal CD8 responses in CD8 T cells; and is thought to be involved in T cell-tumor cell interaction.
Abbreviation
4-1BBL; TNFSF9
Endotoxin
< 0.1 EU per μg of the protein as determined by the LAL method.
Reconstitution
Please refer to the printed manual for detailed information.
Formulation
Lyophilized from sterile PBS, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Activity
Measure by its ability to induce IL-8 secretion in human PBMCs. The ED50 for this effect is 1-5 ng/mL.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 ug
Available: In stock
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