Comparison

Recombinant Human Tau-D Protein (His Tag)

Item no. ELS-PKSH032757-50ug
Manufacturer Elabscience
Amount 50 ug
Quantity options 10 ug 50 ug
Category
Type Proteins
Format Lyophilized Powder
Specific against Human (Homo sapiens)
Host E.coli
Conjugate/Tag HIS
Purity > 80 % as determined by reducing SDS-PAGE.
Sequence Gln249-Gln381
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias MAPT, MAPTL, MTBT1, Microtubule-Associated Protein Tau, Neurofibrillary Tangle Protein, PHF-Tau, Paired Helical Filament-Tau, TAU
Similar products MAPT, TAU, MAPTL, MTBT1, Microtubule-Associated Protein Tau, Neurofibrillary Tangle Protein, Paired Helical Filament-Tau, PHF-Tau
Shipping Condition Cool pack
Available
Manufacturer - Category
Recombinant Proteins / Others
Manufacturer - Conjugate / Tag
C-His
Shipping Temperature
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
15.4 kDa
Observed Molecular Weight
16 kDa
Manufacturer - Research Areas
Neuroscience, Signal Transduction
Background
Microtubule-Associated Protein TAU is abundantly expressed in neurons of the central nervous system and less commonly expressed elsewhere, but is also expressed at very low levels in CNS astrocytes and oligodendrocytes. Tau interacts with tubulin to stabilize microtubules and promotes tubulin assembly into microtubules. The C-terminus of TAU binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau acts as a linker protein. When tau is defective, and no longer stabilize microtubules properly, it can result in dementias such as Alzheimer's disease and other tauopathies.
Abbreviation
Tau-D
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Reconstitution
Please refer to the printed manual for detailed information.
Formulation
Lyophilized from a 0.2 μm filtered solution of PBS, 1mM PMSF, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Activity
Not validated for activity

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 ug
Available: In stock
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