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Recombinant Human TRAIL R3/TNFRSF10C Protein (Fc & His Tag)

Recombinant Human TRAIL R3/TNFRSF10C Protein (Fc & His Tag)

Item no.	ELS-PKSH033129-50ug
Manufacturer	Elabscience
Amount	50 ug
Quantity options	10 ug 50 ug
Category	Oncology Neuroscience Neuroinflammation Metabolism Diabetes Neural Epigenetics By Cell Type Carcinoma Hematology Lymphoma Melanoma Sarcoma Peptides & Proteins Recombinant Proteins Cell Biology Obesity Cell Culture Cytokines Cell Status Necrosis Apoptosis Cardiovascular Research Ischemia & Reperfusion Injury
Type	Proteins
Format	Lyophilized Powder
Specific against	Human (Homo sapiens)
Host	HEK293 cells
Conjugate/Tag	HIS, Fc
Purity	> 95 % as determined by reducing SDS-PAGE.
Sequence	Ala26-Ala221
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Antagonist Decoy Receptor for TRAIL/Apo-2L, DcR1, Decoy Receptor 1, Decoy TRAIL Receptor Without Death Domain, Lymphocyte Inhibitor of TRAIL, TNF-Related Apoptosis-Inducing Ligand Receptor 3, TRAIL Receptor , Tumor Necrosis Factor Receptor Superfamily Member 10C
Similar products	DcR1, TNFRSF10C, TRAIL-R3, DCR1, TRAILR3, CD263, LIT, TRID, Tumor Necrosis Factor Receptor Superfamily Member 10C, Decoy Receptor 1, Antagonist Decoy Receptor for TRAIL/Apo-2L, Decoy TRAIL Receptor Without Death Domain, Lymphocyte Inhibitor of TRAIL, TNF-Related Apoptosis-Inducing Ligand Receptor 3, TRAIL Receptor 3, TRAIL Receptor Without an Intracellular Domain
Shipping Condition	Cool pack
Available
Manufacturer - Category	Recombinant Proteins / Others
Manufacturer - Conjugate / Tag	C-Fc-His
Shipping Temperature	This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight	48.7 kDa
Observed Molecular Weight	90 kDa
Manufacturer - Research Areas	Cell biology, Cancer, immunology
Background	Tumor Necrosis Factor Receptor Superfamily Member 10C (TNFRSF10C) is a glycosyl-phosphatidylinositol-linked membrane protein which binds TRAIL with high affinity. TNFRSF10C has the TRAIL-binding extracellular cysteine-rich domains; lacks the intracellular signaling domain. As a result; binding of TRAIL to TRAIL R3 doesn’t transduce an apoptosis signal. The expression of TRAIL R3 gene has been shown to protect cells bearing TRAIL R1 and/or TRAIL R2 from TRAIL-induced apoptosis.
Abbreviation	TRAIL R3; TNFRSF10C
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method.
Reconstitution	Please refer to the printed manual for detailed information.
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Activity	Not validated for activity
Protein Construction	Recombinant Human TNF-Related Apoptosis-Inducing Ligand Receptor 3 is produced by our Mammalian expression system and the target gene encoding Ala26-Ala221 is expressed with a Fc; 6His tag at the C-terminus.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

ELS-PKSH033129-50ug-datasheet.pdf

ELS-PKSH033129-50ug-safety-datasheet.pdf