Item no. |
ELS-PKSH033172-10ug |
Manufacturer |
Elabscience
|
Amount |
10 ug |
Quantity options |
10 ug
50 ug
|
Category |
|
Type |
Proteins |
Format |
Lyophilized Powder |
Specific against |
Human (Homo sapiens) |
Host |
E.coli |
Conjugate/Tag |
HIS |
Purity |
> 90 % as determined by reducing SDS-PAGE. |
Sequence |
Met 1-Tyr133 |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
CASM, Cancer-Associated Sm-Like, LSM1, Small Nuclear Ribonuclear CaSm, U6 snRNA-Associated Sm-Like Protein LSm1 |
Similar products |
LSM1, CASM, U6 snRNA-Associated Sm-Like Protein LSm1, Cancer-Associated Sm-Like, Small Nuclear Ribonuclear CaSm |
Shipping condition |
Cool pack |
Available |
|
Manufacturer - Category |
Recombinant Proteins / Others |
Manufacturer - Conjugate / Tag |
C-His |
Shipping Temperature |
This product is provided as lyophilized powder which is shipped with ice packs. |
Storage Conditions |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
Calculated Molecular Weight |
16.2 kDa |
Observed Molecular Weight |
19 kDa |
Research Areas |
Tags & Cell Markers, epigenetics and nuclear signal |
Background |
U6 snRNA-Associated Sm-Like Protein LSm1 (LSM1) belongs to the snRNP Sm proteins family. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which plays an important role in pre-mRNA splicing. LSM1 binds specifically to the 3-terminal U-tract of U6snRNA. LSM1 can interact with SLBP when histone mRNA is being rapidly degraded during the S phase. In addition, LSM1 is associated with cellular transformation and the progression of several malignancies including mesothelioma, lung cancer and breast cancer. |
Abbreviation |
LSM1 |
Endotoxin |
< 1.0 EU per μg of the protein as determined by the LAL method. |
Reconstitution |
Please refer to the printed manual for detailed information. |
Formulation |
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
Activity |
Not validated for activity |
Protein Construction |
Recombinant Human U6 snRNA-Associated Sm-Like Protein LSm1 is produced by our E.coli expression system and the target gene encoding Met1-Tyr133 is expressed with a 6His tag at the C-terminus. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.