Item no. |
ELS-PKSH033401-50ug |
Manufacturer |
Elabscience
|
Amount |
50 ug |
Quantity options |
10 ug
50 ug
|
Category |
|
Type |
Proteins |
Format |
Lyophilized Powder |
Specific against |
Human (Homo sapiens) |
Host |
HEK293 cells |
Conjugate/Tag |
HIS, Fc |
Purity |
> 95 % as determined by reducing SDS-PAGE. |
Sequence |
Gln27-Ser220 |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
B-lymphocyte activation marker BLAST-1, BCM1, BCM1 surface antigen, BLAST1, CD48, CD48 antigen, Leukocyte antigen MEM-102, SLAMF2, TCT.1, hCD48, mCD48 |
Similar products |
SLAMF2, CD48, BCM1, BLAST1, hCD48, mCD48, B-lymphocyte activation marker BLAST-1, BCM1 surface antigen, CD48 antigen, Leukocyte antigen MEM-102, TCT.1 |
Shipping condition |
Cool pack |
Available |
|
Manufacturer - Category |
Recombinant Proteins / Immune Checkpoint Proteins |
Manufacturer - Conjugate / Tag |
C-Fc-His |
Shipping Temperature |
This product is provided as lyophilized powder which is shipped with ice packs. |
Storage Conditions |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
Calculated Molecular Weight |
50.3 kDa |
Observed Molecular Weight |
71 kDa |
Research Areas |
immunology |
Background |
CD48 antigen; also known as B-lymphocyte activation marker BLAST-1; BCM1 surface antigen; Leukocyte antigen MEM-102; TCT.1; CD48; BCM1; and BLAST1; CD48 contains one Ig-like C2-type domain and one Ig-like V-type domain; but does not have a transmembrane domain; however; but is held at the cell surface by a GPI anchor via a C-terminal domain which maybe cleaved to yield a soluble form of the receptor. CD48 may facilitate interaction between activated lymphocytes and be involved in regulating T-cell activation. CD48 plays a vital role as an environmental sensor for regulating progenitor cell numbers and inhibiting tumor development. It is suggested that the anti-CD48 mAb has the potential to become an effective therapeutic mAb against multiple myeloma. |
Abbreviation |
CD48 |
Endotoxin |
< 1.0 EU per μg of the protein as determined by the LAL method. |
Reconstitution |
Please refer to the printed manual for detailed information. |
Formulation |
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
Activity |
Not validated for activity |
Protein Construction |
Recombinant Human SLAM Family Member 2 is produced by our Mammalian expression system and the target gene encoding Gln27-Ser220 is expressed with a Fc; 6His tag at the C-terminus. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.