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Recombinant Human ALK-1/ACVRL1 Protein (Fc Tag)

Recombinant Human ALK-1/ACVRL1 Protein (Fc Tag)

Item no.	ELS-PKSH033782-10ug
Manufacturer	Elabscience
Amount	10 ug
Quantity options	10 ug 50 ug
Category	Neuroscience Molecular Targets for Neuroscience Peptides & Proteins Recombinant Proteins
Type	Proteins
Format	Lyophilized Powder
Specific against	Human (Homo sapiens)
Host	HEK293 cells
Conjugate/Tag	Fc
Purity	> 90 % as determined by reducing SDS-PAGE.
Sequence	Asp22-Gln118
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	ACVRL1, ACVRLK1, ALK-1, ALK1, Activin Receptor-Like Kinase 1, HHT, HHT2, ORW2, SKR3, Serine/Threonine-Protein Kinase Receptor R3, TGF-B Superfamily Receptor Type I, TSR-I
Similar products	ACVRL1, ACVRLK1, ALK1, HHT2, ALK-1, HHT, ORW2, SKR3, TSR-I, Serine/Threonine-Protein Kinase Receptor R3, TGF-B Superfamily Receptor Type I, Activin Receptor-Like Kinase 1
Shipping Condition	Cool pack
Available
Manufacturer - Category	Recombinant Proteins / Others
Manufacturer - Conjugate / Tag	C-Fc
Shipping Temperature	This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight	37.6 kDa
Observed Molecular Weight	50-65 kDa
Manufacturer - Research Areas	Signal Transduction, Cardiovascular, Cancer, metabolism,
Background	Activin Receptor-Like Kinase 1 (ALK-1) is a type I cell-surface receptor for the TGF-βsuperfamily of ligands. ALK-1 has a high degree of similarity in serine-threonine kinase subdomains, a glycine and serine rich region preceding the kinase-domain, and a C-terminal tail with other activin receptor-like kinase proteins. The mutations of ALK-1 are associated with Rendu-Osler-Weber syndrome 2, this suggests ACVRL1 is associated with blood vessel development and repair.
Abbreviation	ALK-1; ACVRL1
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method.
Reconstitution	Please refer to the printed manual for detailed information.
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Activity	Not validated for activity
Protein Construction	Recombinant Human ALK-1 is produced by our Mammalian expression system and the target gene encoding Asp22-Gln118 is expressed with a Fc tag at the C-terminus.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

ELS-PKSH033782-10ug-datasheet.pdf

ELS-PKSH033782-10ug-safety-datasheet.pdf