« Back
Home /
Recombinant Mouse OMGP/OMG Protein (aa 1-245, His Tag)

Recombinant Mouse OMGP/OMG Protein (aa 1-245, His Tag)

Item no.	ELS-PKSM040549-50ug
Manufacturer	Elabscience
Amount	50 ug
Quantity options	20 ug 50 ug
Category	Oncology Neuroscience Metabolism Diabetes Molecular Targets for Neuroscience Neural Signaling By Cell Type Blastoma Peptides & Proteins Recombinant Proteins
Type	Proteins
Format	Lyophilized Powder
Specific against	Mouse (Murine, Mus musculus)
Host	HEK293 cells
Conjugate/Tag	HIS
Purity	> 95 % as determined by reducing SDS-PAGE.
Sequence	Met 1-Thr 245
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	LNGFR, RP23-67E18.6, Tnfrsf16, p75, p75NGFR, p75NTR
Similar products	p75, p75NTR, LNGFR, Tnfrsf16, p75NGFR, RP23-67E18.6
Shipping Condition	Cool pack
Available
Manufacturer - Category	Recombinant Proteins / Others
Manufacturer - Conjugate / Tag	C-His
Shipping Temperature	This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight	27.0 kDa
Observed Molecular Weight	44 kDa
Background	Oligodendrocyte-myelin glycoprotein, also known as OMG and OMGP, is a cell membrane protein which contains eightLRR (leucine-rich) repeats. OMG / OMGP is a glycosylphosphatidylinositol-anchored protein expressed by neurons and oligodendrocytes in the central nervous system (CNS). OMG / OMGP is a cell adhesion molecule contributing to the interactive process required for myelination in the central nervous system. OMG / OMGP play roles in both the developing and adult central nervous system. OMG / OMGP participats in growth cone collapse and inhibition of neurite outgrowth through its interaction with NgR, the receptor for Nogo. This function requires its leucine-rich repeat domain, a highly conserved region in OMgp during mammal evolution. OMG / OMGP leucine-rich repeat domain is also implicated in the inhibition of cell proliferation. OMG / OMGP may also be involved in the formation and maintenance of myelin sheaths. Cell proliferation, neuronal sprouting and myelination are crucial processes involved in brain development and regeneration after injury.
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method.
Reconstitution	Please refer to the printed manual for detailed information.
Formulation	Lyophilized from sterile PBS, pH 7.4 Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Activity	Not validated for activity

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

ELS-PKSM040549-50ug-datasheet.pdf

ELS-PKSM040549-50ug-safety-datasheet.pdf