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Recombinant Mouse Semaphorin-4D/SEMA4D Protein (His Tag)

Recombinant Mouse Semaphorin-4D/SEMA4D Protein (His Tag)

Item no.	ELS-PKSM040568-100ug
Manufacturer	Elabscience
Amount	100 ug
Quantity options	100 ug 50 ug
Category	Oncology Neuroscience Neural Adhesion Molecules By Cell Type Peptides & Proteins Recombinant Proteins
Type	Proteins
Format	Lyophilized Powder
Applications	ELISA
Specific against	Mouse (Murine, Mus musculus)
Host	HEK293 cells
Conjugate/Tag	HIS
Purity	> 96 % as determined by reducing SDS-PAGE.
Sequence	Met 1-Arg 733
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	CD100, M-Sema G, SEMA4D, Sema J, Semacl2, Semaj, Semaphorin-4D, Semaphorin-C-like 2, Semaphorin-J, coll-4
Similar products	SEMA4D, CD100, coll-4, Semacl2, Semaphorin-4D, M-Sema G, Semaphorin-C-like 2, Semaphorin-J, Sema J, Semaj
Shipping Condition	Cool pack
Available
Manufacturer - Category	Recombinant Proteins / Others
Manufacturer - Conjugate / Tag	C-His
Shipping Temperature	This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight	80.2 kDa
Observed Molecular Weight	100-110 kDa
Background	Semaphorin 4D (SEMA4D or CD1) is a member of the semaphorin family of proteins and an important mediator of the movement and differentiation of multiple cell types, including those of the immune, vascular, and nervous systems. VEGF and SEMA4D had a positive correlation with the malignant degree of ovarian cancer, and SEMA4D can serve as an independent prognostic factor. SEMA4D was the first semaphorin described to have immune functions and serves important roles in T cell priming, antibody production, and cell-to-cell adhesion. Proteolytic cleavage of SEMA4D from the cell surface gives rise to a soluble fragment of SEMA4D (sSEMA4D). Similar to the transmembranal form, sSEMA4D is thought to have immunoregulatory properties.
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method.
Reconstitution	Please refer to the printed manual for detailed information.
Formulation	Lyophilized from sterile PBS, pH 7.4 Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Activity	Measured by its ability to bind human SEMA4A in a functional ELISA.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

ELS-PKSM040568-100ug-datasheet.pdf

ELS-PKSM040568-100ug-safety-datasheet.pdf