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Recombinant Mouse EpCAM/TROP-1 Protein (His Tag)

Recombinant Mouse EpCAM/TROP-1 Protein (His Tag)

Item no.	ELS-PKSM040591-50ug
Manufacturer	Elabscience
Amount	50 ug
Quantity options	100 ug 50 ug
Category	Oncology Neuroscience Neuroinflammation Molecular Targets for Neuroscience Neural Signaling Protein Aggregation, Clearance & Misfolding By Cell Type Blastoma Carcinoma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Peptides & Proteins Recombinant Proteins By Organ Colorectal Cancer Heart & Blood Cancer Thyroid Cancer
Type	Proteins
Format	Lyophilized Powder
Specific against	Mouse (Murine, Mus musculus)
Host	HEK293 cells
Conjugate/Tag	HIS
Purity	> 95 % as determined by reducing SDS-PAGE.
Sequence	Met 1-Thr 266
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	CD326, E, EGP, EGP-2, Epithelial cell adhesion molecule, Neurotrophic tyrosine kinase receptor-related 1, ROR1, TROP1, Tumor-associated calcium signal transducer 1, receptor tyrosine kinase-like orphan receptor 1, tyrosine-protein kinase transmembrane receptor ROR1
Similar products	ROR1, GA733-2, TROP1, Epithelial cell adhesion molecule, EGP, EGP-2, Ep-CAM, gp40, CD326, Tumor-associated calcium signal transducer 1, Ly74, Egp314, EpCAM1, Tacsd1, Tacstd1, Neurotrophic tyrosine kinase receptor-related 1, receptor tyrosine kinase-like orphan receptor 1, tyrosine-protein kinase transmembrane receptor ROR1
Shipping Condition	Cool pack
Available
Manufacturer - Category	Recombinant Proteins / Others
Manufacturer - Conjugate / Tag	C-His
Shipping Temperature	This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight	29 kDa
Observed Molecular Weight	37 kDa
Background	Epithelial Cell Adhesion Molecule (EpCAM), also known as GA733-2 antigen, is a type â … transmembrane glycoprotein composed of an extracellular domain with two EGF-Like repeats and a cystenin-rich region, a transmembrane domain and a cytoplasmic domain. It modulates cell adhesion and proliferation. Its overexpression has been detected in many epithelial tumours and has been associated with high stage, high grade and a worse survival in some tumour types. EpCAM has been shown to function as a calcium-independent homophilic cell adhesion molecule that does not exhibit any obvious relationship to the four known cell adhesion molecule superfamilies. However, recent insights have revealed that EpCAM participates in not only cell adhesion, but also in proliferation, migration and differentiation of cells. In addition, recent study revealed that EpCAM is the Wnt-beta-catenin signaling target gene and may be used to facilitate prognosis. It has oncogenic potential and is activated by release of its intracellular domain, which can signal into the cell nucleus by engagement of elements of the wnt pathway.
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method.
Reconstitution	Please refer to the printed manual for detailed information.
Formulation	Lyophilized from sterile PBS, pH 7.4 Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Activity	Not validated for activity

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

ELS-PKSM040591-50ug-datasheet.pdf

ELS-PKSM040591-50ug-safety-datasheet.pdf