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Recombinant Mouse EphB4/HTK Protein (Fc Tag)

Recombinant Mouse EphB4/HTK Protein (Fc Tag)

Item no.	ELS-PKSM040599-200ug
Manufacturer	Elabscience
Amount	200 ug
Quantity options	100 ug 200 ug
Category	Oncology By Cell Type Carcinoma Melanoma Sarcoma Peptides & Proteins Recombinant Proteins Mesothelioma
Type	Proteins
Format	Lyophilized Powder
Applications	ELISA
Specific against	Mouse (Murine, Mus musculus)
Host	HEK293 cells
Conjugate/Tag	C-hFc
Purity	> 97 % as determined by reducing SDS-PAGE.
Sequence	Met 1-Ala 539
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	AI042935, Htk, MDK2, Myk1, Tyro11
Similar products	Htk, Myk1, AI042935, MDK2, Tyro11
Shipping Condition	Cool pack
Available
Manufacturer - Category	Recombinant Proteins / Others
Manufacturer - Conjugate / Tag	C-hFc
Shipping Temperature	This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight	84.7 kDa
Observed Molecular Weight	110 kDa
Background	Ephrin type-B receptor 4 is a protein that in humans is encoded by the EPHB4 gene. It is a single-pass type I membrane protein belonging to the ephrin receptor subfamily of protein kinase superfamily. Members of the ephrin and Eph family are local mediators of cell function through largely contact-dependent processes in development and in maturity. Furthermore, EphB4 protein and the corresponding ligand Ephrin-B2 contribute to tumor growth in various human tumors. EphB4 protein has tumor suppressor activities and that regulation of cell proliferation, extracellular matrix remodeling, and invasive potential are important mechanisms of tumor suppression. Therefore, Ephrin-B2/EphB4 may be recognized as a novel prognostic indicator for cancers.
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method.
Reconstitution	Please refer to the printed manual for detailed information.
Formulation	Lyophilized from sterile PBS, pH 7.4 Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Activity	Immobilized mouse EPHB2-His at 10 μg/mL (100 μl/well) can bind mouse EPHB4-Fc, The EC50 of mouse EPHB4-Fc is 15 ng/mL.
Protein Construction	A DNA sequence encoding the mouse EPHB4 (P54761-1) extracellular domain (Met 1-Ala 539) was fused with the Fc region of human IgG1 at the C-terminus.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

ELS-PKSM040599-200ug-datasheet.pdf

ELS-PKSM040599-200ug-safety-datasheet.pdf