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Recombinant Mouse CD155/PVR Protein (aa 1-345, His Tag)

Recombinant Mouse CD155/PVR Protein (aa 1-345, His Tag)

Item no.	ELS-PKSM040773-100ug
Manufacturer	Elabscience
Amount	100 ug
Quantity options	100 ug 50 ug
Category	Neuroscience Neural Adhesion Molecules Peptides & Proteins Recombinant Proteins
Type	Proteins
Format	Lyophilized Powder
Applications	ELISA
Specific against	Mouse (Murine, Mus musculus)
Host	HEK293 cells
Conjugate/Tag	HIS
Purity	> 97 % as determined by reducing SDS-PAGE.
Sequence	Met 1-Arg 345
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	3830421F03Rik, CD155, CD155 antigen, D7Ertd458e, HVED, Necl5, Nectin-2, Nectin-like protein 5, PVR, PVS, Poliovirus receptor, Pvr, Taa1, Tage4 , Tage4 receptor, mE4, necl-5
Similar products	PVR, PVS, Poliovirus receptor, Nectin-like protein 5, CD155, HVED, Nectin-2, Taa1, CD155 antigen, Pvr, Tage4, mE4, Necl5, Tage4 receptor, 3830421F03Rik, D7Ertd458e, necl-5
Shipping condition	Cool pack
Available
Manufacturer - Category	Recombinant Proteins / Immune Checkpoint Proteins
Manufacturer - Conjugate / Tag	C-His
Shipping Temperature	This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Calculated Molecular Weight	28.0 kDa
Observed Molecular Weight	60-65 kDa
Background	CD155, commonly known as PVR (poliovirus receptor) and Necl-5 (nectin-like molecule-5), is a type I transmembrane single-span glycoprotein, and belongs to the nectins and nectin-like (Necl) subfamily. CD155 was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV), an etiologic agent of the central nervous system disease poliomyelitis. The normal cellular function is in the establishment of intercellular adherens junctions between epithelial cells. CD155 may assist in an efficient humoral immune response generated within the intestinal immune system. It has been demonstrated that CD155 can be recognized and bond by DNAM-1 and CD96 which promote the adhension, migration and NK-cell killing, and thus efficiently prime cell-mediated tumor-specific immunity.
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method.
Reconstitution	Please refer to the printed manual for detailed information.
Formulation	Lyophilized from sterile PBS, pH 7.4 Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Activity	Measured by its ability to bind recombinant mouse CD226/DNAM-1. Immobilized recombinant mouse CD155/PVR at 1 μg/ml (100 μl/well) can bind recombinant mouse CD226/DNAM-1 with a linear range of 0.78-100 ng/ml.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 7/10/2025

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