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Recombinant Mouse S100A11 Protein (His Tag)

Recombinant Mouse S100A11 Protein (His Tag)

Item no.	ELS-PKSM040794-100ug
Manufacturer	Elabscience
Amount	100 ug
Quantity options	100 ug 20 ug
Category	Oncology Neuroscience Neural Lineage Markers Neuroinflammation Molecular Targets for Neuroscience Targets for Rodent Neurosciences By Cell Type Melanoma Peptides & Proteins Recombinant Proteins Cytoskeleton Markers
Type	Proteins
Format	Lyophilized Powder
Specific against	Mouse (Murine, Mus musculus)
Host	E.coli
Conjugate/Tag	HIS
Purity	> 90 % as determined by reducing SDS-PAGE.
Sequence	Met1-Ile98
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Calgizzarin, EMAP, EMAPI, Emap1, Endothelial monocyte-activating polypeptide, Protein S100-A11, Protein S100-C, S100 calcium-binding protein A11, S100A11, S100a11, S100a14, S100c, cal
Similar products	EMAP, S100A11, S100a11, S100a14, Calgizzarin, Protein S100-A11, Protein S100-C, S100 calcium-binding protein A11, Endothelial monocyte-activating polypeptide, S100c, cal, Emap1, EMAPI
Shipping Condition	Cool pack
Available
Manufacturer - Category	Recombinant Proteins / Others
Manufacturer - Conjugate / Tag	N-His
Shipping Temperature	This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight	13.2 kDa
Observed Molecular Weight	14 kDa
Background	Protein S100-A11, also known as S100 calcium-binding protein A11, S100A11 and MLN70, is a member of theS-100 family. S100A11 is widely expressed in multiple tissues, and is located in cytoplasm, nucleus, and even cell periphery. S100A11 exists as a non-covalent homodimer with an antiparallel conformation. Ca(2+) binding to S100A11 would trigger conformational changes which would expose the hydrophobic cleft of S100A11 and facilitate its interaction with target proteins. As a dual cell growth mediator, S100A11 acts as either a tumor suppressor or promoter in many different types of tumors and would play respective roles in influencing the proliferation of the cancer cells. In the nucleus, S100A11 suppresses the growth of keratinocytes through p21 (CIP1/WAF1) activation and induces cell differentiation. S100A11 is also a novel diagnostic marker in breast carcinoma.
Endotoxin	Please contact us for more information.
Reconstitution	Please refer to the printed manual for detailed information.
Formulation	Lyophilized from sterile PBS, 10% glycerol, pH 7.4 Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Activity	Not validated for activity
Protein Construction	A DNA sequence encoding the mouse S100A11 (NP_058020.1) (Met1-Ile98) was expressed with a polyhistidine tag at the N-terminus.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

ELS-PKSM040794-100ug-datasheet.pdf

ELS-PKSM040794-100ug-safety-datasheet.pdf